Do NSAIDs impede fracture healing?

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Do NSAIDs impede fracture healing?

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Title: Do NSAIDs impede fracture healing?
Author: Yates, Jennifer E.; Shah, Syed Hadi; Blackwell, Jean
Keywords: pain relief
bone formation
Date: 2011-01
Publisher: Family Physicians Inquiries Network
Citation: Journal of Family Practice, 60(1) 2011: 41-42.
Abstract: Nonsteroidal anti-inflammatory drugs (NSAIDs) don't appear to impair clinical fracture healing (strength of recommendation [SOR]: B, inconsistent evidence from a randomized controlled trial [RCT] and retrospective studies). Even though animal studies show delayed healing and nonunion with NSAID use, evidence in humans doesn't merit avoiding NSAIDs in patients with fractures who need the drugs' analgesic and anti-inflammatory benefits.
URI: http://hdl.handle.net/10355/9953

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