Browsing Chemistry Electronic Theses and Dissertations (UMKC) by Thesis Semester "2014 Spring"
Now showing items 1-8 of 8
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Design, synthesis, characterization and photovoltaic applications of conjugated polymer hybrids containing coordinatively binded semiconducting nanocrystals
(2014-07-17)Orgainc-inorganic hybrids containing organic conjugated polymers and inorganic semiconducting nanocrystals are fascinating optoelectronic materials which may combine the advantages of both worlds. This dissertation aims ... -
Development of polymeric nanoparticulate formulation encapsulating protein molecules following hydrophobic ion pairing complexation
(2014)Several formulation strategies have been employed to enable sustained delivery of antibody therapeutics by nanoparticulate based dosage forms. However, development of sustained release nanoparticulate based dosage form for ... -
Evaluation of therapeutic effect of PCBP2 siRNA on hepatic stellate cells and development of a streptavidin-based siRNA delivery system
(2014)Type I collagen accumulates during liver fibrosis primarily because α-complex protein-2 (αCP2), encoded by the poly(rC) binding protein 2 (PCBP2) gene, binds to the 3′end of the collagen mRNA and increases its half-life. ... -
Polycyclic Aromatic Hydrocarbon (PAH)-Based Conjugated Macrocycles and Polymers For Electronic Applications
(2014)Due to the high tendency to form π-stacked ordered phases, polycyclic aromatic hydrocarbons (PAHs) are attractive building blocks for the assembly of conjugated systems for electronic applications. The body of this ... -
Protein production and applications of NMR in pharmaceutical sciences
(2014-08-28)The objective of Part I (Protein production for structural elucidation using NMR) is to design and develop strategies of producing amyloid beta protein for structural analysis using NMR. Amyloid beta oligomers are considered ... -
Raman, Infrared and Microwave Spectra, Conformational Stability, R₀ Structural Parameters and Vibrational Assignments of Some Organoamines, Organophosphines, Alcohols And Substituted Four And Five Membered Rings
(2014)The infrared and Raman spectra of compounds with amino, phosphours, silane and hydroxyl functional groups, as well as some with cyclic skeletal structures have been recorded of the gas and in condensed phases. Temperature ... -
Ritonavir - A Novel Multidrug Resistance Modulator in Cancer Chemotherapy and Ocular Neovascular Diseases
(2014-08-28)Multidrug resistance (MDR), a clinical outcome characterized by subtherapeutic intracellular drug concentration, is one of the predominant factors limiting effective cancer chemotherapy. Several possible mechanisms and ... -
Role of Membrane Transporters in Drug Delivery, Drug Disposition And Drug-Drug Interactions
(2014-08-28)Tissues such as liver, kidney, brain and intestine expresses membrane transporters which play a vital role in drug absorption, distribution, metabolism and excretion. Understanding of functionality and molecular expression ...