Browsing Cell Biology and Biophysics Electronic Theses and Dissertations (UMKC) by Thesis Semester "2013 Fall"
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HIV-1 gp120 and Methamphetamine-mediated Induction of Proinflammatory Cytokines/chemokines and Oxidative Stress in Astrocytes: Implications in Neuroinflammation
(2014-04-02)HIV associated neurocognitive disorder (HAND) remains a major concern for patients infected with HIV. The viral envelope protein, gp120 has been extensively studied and some of its neurotoxic effects are due to the increased ... -
The Middle Region is Required for Phosphorylation Regulation of Ceramide Transfer Protein
(2013)The trafficking of ceramide from endoplasmic reticulum (ER), where it is synthesized, to the Golgi for sphingomyelin synthesis is mediated by the ceramide transfer protein (CERT) in a nonvesicular fashion. CERT is a cytosolic ... -
The Role of Host Translation Initiation Factors eIF4H and eIF4A and the Exon Junction Complex in the Control of mRNA turnover and Translation by the Virion Host Shut off Protein of Herpes Simplex Virus
(2013)During lytic infections, the HSV Vhs endonuclease (UL41) degrades many viral and cellular mRNAs. This endonuclease activity is dependent upon the ability of Vhs to bind the host translation initiation factors eIF4AI/II and ...