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The function of Drosophila Integrin-Dim7-Elmo-Mbc→Rac signaling pathway in the muscle attachment formation and maintenance
(2013)
The Engulfment and Cell Motility (Elmo)-(Myoblast city) Mbc→Rac signaling pathway is evolutionarily conserved from C. elegans to vertebrates and is essential for many developmental processes, including phagocytosis and ...
Independent Functions Of Clueless In Differential Integrin Secretion And Mitochondrial Quality Control In Drosophila Muscle
(2015)
Drosophila Clueless (Clu) and its conserved orthologs are known for their role in the prevention of mitochondrial clustering. Here, we uncover its independent roles in the delivery of integrin subunits and the regulation ...
Determining the differential roles of the dock family of GEFs in drosophila development
(2015-05-19)
The evolutionarily conserved Dock proteins function as unconventional guanine
nucleotide exchange factors (GEFs). Upon binding to ELMO (Engulfment and cell
motility) proteins, Dock-ELMO complexes activate the Rho family ...