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The MOspace Institutional Repository is an online repository for creative and scholarly works and other resources created by faculty, students, and staff at the University of Missouri--Columbia and the University of Missouri--Kansas City. MOspace makes these resources freely available on the web and assures their preservation for the future.
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Item RNA-seq raw data(2025)Item IHE APPLI Guidebook : a customizable model for embedding research development support within a grant competition(University of Missouri--Columbia, 2025)Our nation’s security and economic prosperity are inextricably linked to the success and competitiveness of U.S.-based science; therefore, all available assets should be directed toward strengthening our leadership in research and innovation. Emerging research institutions (ERIs) include more than 2,600 colleges and universities. Yet, federally-funded research projects are increasingly concentrated at a small number of institutions with very high research activity (R1s). In order to engage the full range of academic and workforce resources, new grant-making and distribution approaches must be explored. In recognition of this need, the U.S. National Science Foundation (NSF) launched the Enabling Partnerships to Increase Innovation Capacity (EPIIC) program in 2023. The program’s key innovation was the utilization of brief, intensive research-development and proposal-preparation support during a live grant contest. Program officers worked with consultants, guest speakers and peer mentors to provide support in three phases: (1) Participant Selection; (2) Challenge Identification and Solution Design; and (3) Proposal Preparation and Submission. The first three cycles of EPIIC were conducted as an iterative design process. The first cycle served to demonstrate its feasibility, while the second and third cycles allowed for testing and refinement of content, pacing, and other aspects of programming. Factors affecting participant engagement and personnel responsibilities were also revised. Successful and broadly applicable aspects of the EPIIC program were documented in order to clarify and disseminate a new, customizable model that could be incorporated into other grant-making programs. The model was named Institution of Higher Education (IHE) Assistance with Proposal Preparation to Leverage Ingenuity (IHE APPLI). This document aims to share promising practices that make up the core components of the EPIIC program— and thus, of the IHE APPLI model. Emerging practices that can be explored as “encouraged” or “optional” enhancements to future applications of the model are also presented. Contents include quick-start resources; the rationale for exploring new award-making approaches; a detailed account of the EPIIC program, which established and tested the model; and advice for customizing the IHE APPLI model during future implementations. Together, these sections form a guidebook designed to enhance, inform, and encourage new approaches within grant programs that support institutional capacity building among ERIs. It is not intended to serve as a definitive publication on this topic. Rather, it is offered as a wayfinding resource to initiate and support further exploration into novel grant-making programs.Item Canine leptospirosis surveillance : a one health framework to improve Puerto Rico leptospirosis surveillance system(University of Missouri--Columbia, 2025)Background: Leptospirosis is a zoonotic disease that has been a public health issue worldwide for many years. The disease is commonly found in tropical and subtropical areas. In the Caribbean, leptospirosis remains endemic, particularly in the island of Puerto Rico, where a surge of cases is seen after natural disasters such as tropical storms and hurricanes. Puerto Rico has a leptospirosis surveillance system that closely monitors disease trends among humans. As of 2024, most cases on the island were associated with exposure to infected animals, nonetheless, the system lacks specifications on which animals the infected cases were exposed to, primarily the most common domestic animal reservoir, such as dogs. Objectives: To evaluate Puerto Rico current leptospirosis surveillance system and to propose a recommendation for implementing a One Health surveillance system on the island that includes canine leptospirosis. Methods: A systematic literature review of canine leptospirosis surveillance systems in the United States was conducted. The search was done across databases (PubMed, ScienceDirect, University of Missouri) and grey literature platforms (Google Scholar, government agencies, public health departments) for the last 10 years (2015 -2025). After the screening process, four canine surveillance system publications were retrieved from public health departments, and six research publications were retrieved from electronic databases. Following CDC guidelines for evaluating surveillance systems, a quality assessment was conducted of the four retrieved publications on canine leptospirosis surveillance systems. The six research publications were utilized to support the idea of implementing a canine leptospirosis surveillance system in Puerto Rico. Findings: The quality assessment findings showed that three surveillance systems followed the CDC guidelines. The analysis and comparison of the Puerto Rico leptospirosis surveillance system demonstrated that Puerto Rico is capable of implementing a canine leptospirosis surveillance system on the island.Item Improving infection prevention knowledge among BSN nursing students : a multi-modality simulation boot camp program(University of Missouri--Columbia, 2025)Background Healthcare-associated infections (HAIs) contribute significantly to patient morbidity, mortality and cost. Nursing students often struggle to consistently apply infection prevention practices, highlighting the need for experiential learning strategies. This quality improvement project implemented a multi-modality simulation boot camp to improve infection prevention competence and confidence among pre-licensure nursing students. Project objectives included increasing competence measured by the Creighton Competency Evaluation Instrument (CCEI), confidence measured by the Generalized Self- Efficacy (GSE) scale, and performance on the Safety and Infection Control subscale of the ATI Adult Health Medical-Surgical exam. Methods A review of literature supported simulation-based learning as an evidence-based method for improving infection prevention knowledge, skills, and self-efficacy. The intervention was delivered across two semesters and incorporated virtual reality, standardized participants, and task trainers. Faculty received preparatory education on simulation best practices. Evaluation measures included pre- and post-intervention CCEI and GSE scores, student perceptions (SET-M), faculty facilitator surveys, and ATI outcomes. Results Competence significantly improved, with CCEI median scores increasing from 4.0 to 6.0 (Z = -5.43, p < .001, r = .79). Confidence improved by more than 5% (U = 658.50, p < .001, r = .38). The Fall 2025 ATI group score was 58.1%, with 62.7% scoring above the national mean, a 2.2% increase over the 2024 cohort. Student and faculty perceptions were positive. Conclusions A multi-modality simulation boot camp strengthened infection prevention competence, confidence, and standardized exam performance. Continued integration of simulation across the curriculum is recommended to reinforce infection prevention behaviors and support patient safety outcomes. IRB Approval IRB approval through exempt review. Co-Authors Dr. Stefanie Birk, Dr. Anne Heyen, Dr. Stephanie Stewart, Dr. Kathleen Tenrreiro Learning Objective The purpose of this QI project was to improve infection prevention competence and confidence among nursing students by implementing a multi-modality simulation boot camp. Learners will apply lessons from the QI project to inform approaches enhancing infection prevention behaviors and patient safety.Item Discharge planning tool leads to earlier discharges and fewer readmissions : a program evaluation(University of Missouri--Columbia, 2025)
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