Ophthalmology presentations (MU)

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https://hdl.handle.net/10355/7091

Items in this collection are public presentations made by Department of Ophthalmology faculty, staff, and students, either alone or as co-authors, and which may or may not have been published in an alternate format. Items may contain more than one file type.

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    Creation of 'Super Avastin': A New Nanomedicine Approach for the Treatment of PXE and AMD [abstract]
    (2010-02) Shukla, Ravi; Nune, Satish K.; Kannan, Raghuraman; Hainsworth, Dean; Katti, Kattesh V.; University of Missouri (System); Missouri Life Sciences Summit (2010: University of Missouri--Kansas City)
    Nanomedicine is an emerging medical area that utilizes nanoparticles for the detection and treatment of diseases. The ubiquitous place of gold in Nanomedicine stems from its chemical ability to serve in an unoxidized state at the nano size level when most surfaces of other metals get oxidized. In addition to our ongoing interest on the development of hybrid gold nanoparticles for use in imaging and therapy of human cancers, we are also actively interested in the fabrication of biocompatible gold nanoparticles conjugated to Avastin for use in the treatment of choroidal neaovascularization associated with Pseudoxanthoma elasticum (PXE) and age related macular degeneration (AMD) ophthalmic diseases. Herein, we report design and development of Avastin conjugated Gold nanoparticles (Super Avastin) for the treatment of PXE and AMD.
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