Department of Orthopaedic Surgery publications, presentations, and posters (MU)
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Item Effect of NSAID use in the acute phase of skeletally immature bone healing : a prospective, randomized, controlled study(2017) Nuelle, Julia A.V.; Coe, Kelsey; Oliver, Harvey; Cook, James L.; Hoernschemeyer, Daniel G.; Gupta, Sumit K.Non-steroidal anti-inflammatory drugs (NSAIDs) are effective in controlling both post-operative pain and pain associated with orthopaedic injuries. In the pediatric population, they can minimize the need for narcotic pain medications. There is little data on the effects these medications have on long bone healing in the skeletally immature patient with a fracture.--Introduction.Item A quantification of the changes in articular cartilage material properties during the onset of osteoarthritis using stress relaxation testing(2016) Rexwinkle, Joe; Werner, Nikki; Polk, Andrew; Pfeiffer, FerrisThis study aims to quantify the relationship between biomechanical properties of articular cartilage and varying levels of tissue damage. While other studies have investigated the relationship between osteoarthritis and mechanical properties, our study provides a method to achieve accurate and rapid results from a single test on a given sample while minimizing the impact of extraneous factors such as varied strain and pore compression which are common issues in creep tests. The results of our optimization show the expected change in aggregate modulus and permeability with tissue damage and provide the first step in determining a concrete, quantitative relationship between these properties.--Discussion