Electrical Engineering and Computer Science presentations (MU)
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Items in this collection represent public presentations made by Department of Electrical and Computer Engineering faculty, staff, and students, either alone or as co-authors, and which may or may not have been published in an alternate format. Items may contain more than one file type.
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Item Select Scenes from Noah D. Manring's Industrial Seminar for Engineers(2000) Manring, NoahThis video presents clips from Noah Manring's industrial seminar for engineers on hydraulic control systems.Item Robotics and Assistive Technology: A Win-Win Scenario(2010) Tyrer, Harry W.; DeSouza, Guilherme; Gabbert, DarrenThe Robotics and Assistive Technology (RAT) Team is a research collaboration between the University of Missouri-Columbia's Adaptive Computing Technology (ACT) Center and the College of Engineering's Department of Electrical and Computer Engineering. This collaboration has given engineering faculty and students fresh insights into person-centered technology research and development. Project outcomes benefit a unique population of persons with severe mobility impairments. Such projects have included electromyographic control mechanisms for power wheelchair and mobile phone devices. Current research is focusing on semiautonomous aides to daily living. This session will explore what made it work.Item Novel Nanostructured Organosilicate Nanoparticle Coatings for Chem-Bio Sensing [abstract](2010-03) Korampally, Venumadhav, 1972-; Darr, Charles Matthew, 1984-; Polo-Parada, Luis; Gangopadhyay, Keshab; Gangopadhyay, Shubhra; Grant, Sheila Ann; Sobel, Annette; Singh, Balram; University of Missouri (System); Missouri Life Sciences Summit (2010: University of Missouri--Kansas City)We present novel nanostructured organosilicate particulate based films and demonstrate that these materials have a great potential for chemical-biological sensor development. With unprecedented high surface areas (> 1400 m2/g) and optical transparency together with its easy surface functionalization, these materials can be readily interfaced with existing immunoassays for the rapid and trace detection of both chemical and biological warfare agents. The ultra high surface area associated with these films stems from its unique nanostructure consisting of nanoparticles (2-5nm) in a “raspberry” structure in combination with interconnected nanopores (3-10nm). This unique nanostructure has been exploited to immobilize high areal density of sensor probes to improve the sensing performance. Two orders of magnitude increase in binding density was achieved when fluorescently tagged protein A molecules were immobilized upon these surfaces compared to flat substrates (glass and Silicon). Our on-going work applies these materials to develop platforms for multiplexed sensitive detection of biological and chemical agents at point of care for both army and civilian use.Item Shock Wave Based Cell Transfection and Fluorescent Organosilicate Nanoparticles for Targeted Drug Delivery [abstract](2010) Korampally, Madhuri; Apperson, Steven J., 1982-; Korampally, Venumadhav, 1972-; Bok, Sangho, 1972-; Thiruvengadathan, Rajagopalan; Bezmelnitsyn, Andrey; Polo-Parada, Luis; Gangopadhyay, Keshab; Gangopadhyay, Shubhra; University of Missouri (System); Missouri Life Sciences Summit (2010: University of Missouri--Kansas City)Nanotechnology is a multidisciplinary field that has applications in life sciences, alternative energy, national defense, and electronics. In the field of medicine, nanotechnology may enable intelligent drug delivery using multifunctional nanoparticles. Here, we show two technologies that are envisioned to work in tandem to enable targeted detection and treatment. First, a shock wave generator used for cell transfection and drug/particle delivery is presented. Then, fluorescent dye/drug encapsulated organosilicate nanoparticles (OSNP) with functionalized surfaces for targeted delivery are described. The shock wave generator has been successfully used to deliver various molecules and nanoparticle to inside of the cells with very high efficiency and low cell damage. These include dextran (77 kDa), naked plasmid, and dye-doped organosilicate nanoparticles into several types of cells lines including T47-D, HL-60, and MCF-7, and also into tissues including entire chicken heart (at developmental stage 20-30) and chicken spinal cord. Dye doped organosilicate nanoparticle surfaces conjugated to antibodies have been successfully used in immunofluorescence assays. Close examination of the nanostructure of these particles reveal its unique nanoporous structure. These nanoparticles are currently under investigation for drug encapsulation and sustained release. The implication of these technologies is that the OSNP can be used as targeted drug carriers, and the shock wave generator can be used to deliver the OSNP into cells to which the particles attach. The research on shock wave micro-transfector system has been funded by the National Science Foundation Grant Opportunities for Academic Liason with Industries program.Item Applications of Energetic Materials and Copper Oxide Nanorods for Decontamination [abstract](2010-03) Thiruvengadathan, Rajagopalan; Lee, Byung Doo; Smith, Brandon; Sengupta, Shramik; Polo-Parada, Luis; Gangopadhyay, Shubhra; Gangopadhyay, Keshab; University of Missouri (System); Missouri Life Sciences Summit (2010: University of Missouri--Kansas City)We demonstrate the potential of nanoenergetic coatings and CuO nanorods to decontaminate surfaces infected with bacteria. The methods of decontamination include (i) fast combustion of an energetic paint applied on contaminated surfaces and (ii) exploitation of biocidal activity of copper oxide. The success of the first method depends mainly on effective heat transfer to the contaminated surface. For this to happen, the substantial heat produced during the combustion of the energetic coating needs to be sustained for sufficient duration. At the same time, it is necessary to ensure that the contaminated surfaces are not damaged. Our research group has developed suitable energetic composition to realize this goal. A stainless steel substrate contaminated with cultured bacteria grown in standard conditions was spray coated with a thick film of the paint (composed of appropriate weight percent of Al nanoparticles dispersed in a fluoropolymer, THV 220A). After a short drying period, the paint was ignited which self propagated across the substrate typically in few milliseconds. A swab of the remaining ash was taken and an LB agar plate was prepared. The plate was incubated at 37°C for 72 hrs with inspection after every 24 hours. No bacteria had grown after 72 hrs indicating the successful destruction of bacteria. Applicability of this method was further extended to removal of biofilms from different substrates. For certain optimal compositions of the energetic formulations, the flame propagates extremely rapidly across the rest of the surface (in tens of milliseconds on 1” x 3” test surfaces) without damaging the surface and leaves behind charred remains of the biofilm that can be wiped / air blown away. We believe that the flame propagates through a series of events in which nano-particles ignite and reach high temperatures as they burn. The high local temperature destroys the biofilm in its immediate vicinity and also helps to ignite other nanoparticles nearby. However, since the amount of heat released is comparatively less, the underlying material surface remains relatively undamaged. Complete destruction of bio-film with no damage to the underlying material can be achieved only for certain optimal values of nanoparticle size and concentration in the organic solvent, and for certain compositions of the solvent itself. We have been able to successfully formulate such blends. Such blends were used to treat biofilm harboring ~ 107 bacteria / cm2. A burn lasting <1 s reduced the number of bacteria to less than our detectable threshold of 2 bacteria / cm2. We would like to use the technology to remove biofilm formed on the surface of heat exchangers. Biofilm buildup causes the efficiency of heat exchangers to drop by ~30%, and costs associated with taking the exchangers offline and cleaning them accrue to billions of dollars each year. Our initial results from the testing on the biocidal activity of the filtrates consisting of copper and chlorine ions obtained during the production of CuO nanorods shows that the contaminated surfaces can be cleaned effectively. Acknowledgement: We acknowledge the financial support provided by the Leonard Wood Institute (LWI).