2013 Health Sciences Research Day (MU)
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Items in this collection are the posters presented at the 2012 Health Sciences Research Day held at the University of Missouri--Columbia.
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Item Heterotopic gray matter in white matter in a 62 year old(2013) Campbell, Jack; Sramek, Brett; Miller, Douglas C.; Health Sciences Research Day (2013 : University of Missouri)"Heterotopia" describes normal cells in an abnormal location, and in the context of neurobiology, usually refers to neurons or gray matter in the leptomeninges or in periventricular or subcortical white matter, ("Gray Matter Heterotopia"). While once thought to be quite rare, the widespread MRI availability allowed increased recognition of these malformations. Clinically, gray matter heterotopias usually manifest as seizures in the first and second decades of life and may have associated motor and cognitive developmental disturbances. We report a patient with no known prior neurologic history, who developed seizures at the age of 62, which were subsequently determined to be from a subcortical gray matter heterotopia. The patient presented to an outside hospital with episodic confusion thought to represent partial seizures, and also numbness in her left foot, leg, and arm. MRI revealed a thickened corpus callosum and abnormal signal extending into the right cingulate gyrus white matter with an infiltrative appearance suggestive of a glioma or gliomatosis. Stereotactic biopsy demonstrated white matter containing irregular islands of synaptophysin-immunopositive gray matter within which there were large dysplastic neurons. This established a diagnosis of ectopic gray matter in the subcortical white matter. To our knowledge, this is the oldest age at which a person with this congenital condition has experienced onset of related symptoms.Item Implementing a chronic care case management program at MedZou Community Health Clinic(2013) Kochne, Elizabeth L.; Health Sciences Research Day (2013 : University of Missouri)MedZou Community Health Clinic, the University of Missouri's student-coordinated free clinic, has served over 900 uninsured patients since opening in October 2008. The clinic functions as the provider of primary care for most patients. Many MedZou patients, some of whom are non- English speakers, have multiple chronic conditions and frequently require assistance for acute exacerbations of these chronic conditions. Unfortunately, the nature of MedZou's rotating volunteer schedule limits continuity of care for these patients. Additionally, clinic visits for non-English speaking patients are lengthy with the use of interpreter services. These issues highlighted the need for a case management program to improve continuity of care for MedZou patients with chronic medical conditions. This project aimed to (1)Identify MedZou patients who would benefit from enrollment in a case management program and (2) Implement a program to improve continuity of care for MedZou's most medically and socially complicated patients in order to achieve the best health outcomes possible.Item A preliminary osteological analysis of the University of Missouri anatomy osteology collection(2013) Shih, Jamin D.; Maddux, Scott D.; Health Sciences Research Day (2013 : University of Missouri)The University of Missouri Anatomy Osteology Collection consists of 97 human skeletons used extensively for anatomy-based education and research. Despite the size and utility of the collection, no information regarding the demographics of the collection has previously been available. Using standard osteological techniques, a preliminary investigation was initiated to ascertain the sex, age at death, and degree of preservation of each specimen in the collection.