The role of tumor induced immune tolerance by tumor associated macrophages in hepatocellular carcinoma
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Hepatocellular carcinoma (HCC) is a lethal disease with limited treatment options. Immunotherapy is revolutionizing cancer care, but FDA approved immune checkpoint inhibitors still only function in a minority of patients. Elucidating the underlying mechanism is required to improve targeted immunotherapy. This study explores the role of tumor-associated macrophages (TAMs) on tumor growth and tumor-induced immune tolerance.
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.