2019 Health Sciences Research Day (MU)

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https://hdl.handle.net/10355/70586

"More than 200 research projects were on display during the 2019 Health Sciences Research Day. The annual event showcased research from MU undergraduate, medical and nursing students, as well as pre- and post-doctoral trainees. The event featured a range of health research, including gene editing, autism, cancer, diabetes, heart disease, ophthalmology, orthopaedics and end-of-life care. Students displayed their work in the School of Medicine’s Acuff Gallery and Patient-Centered Care Learning Center at the day-long event."--2019 Health Sciences Research Day website (https://medicine.missouri.edu/news/innovations-take-center-stage-health-sciences-research-day), viewed December 4, 2019.

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Now showing 1 - 5 of 5

The role of tumor induced immune tolerance by tumor associated macrophages in hepatocellular carcinoma
(2019) Sauer, Madison; Qi, Xiaoqiang; Staveley-O'Carroll, Kevin; Guangfu, Li
Hepatocellular carcinoma (HCC) is a lethal disease with limited treatment options. Immunotherapy is revolutionizing cancer care, but FDA approved immune checkpoint inhibitors still only function in a minority of patients. Elucidating the underlying mechanism is required to improve targeted immunotherapy. This study explores the role of tumor-associated macrophages (TAMs) on tumor growth and tumor-induced immune tolerance.
Impact of the geriatric patient advocacy and wellness strategy (GeriPAWS) pilot for delirium prevention in acute care surgery patients
(2019) Sauer, Madeline; Gary, Michelle; Craig, Kevin; Quick, Jacob
Seven million patients experience delirium with on 40% receiving diagnosis in the hospital each year. Prevention strategies have been shown to reduce delirium, improve health outcomes, and decrease hospital costs but are challenging to implement in busy healthcare settings. We aim to implement a volunteer-lead program to reduce delirium, improve patient satisfaction, and increase awareness of delirium in elderly patients.
Impact of culture and/or religion on end of life decisions among advanced cancer patients in developing countries
(2019) Yevu Johnson, Justina S.; Alexander, G. L.; Health Sciences Research Day (2019 : University of Missouri)
Introduction: The objective of the study was to identify factors related to culture and/or religion that impact decision making at the end of life. Conclusions: * Improving cancer care in developing countries requires that the culture, traditions, and religious inclinations of healthcare providers, patients, and family, as well as the expert use of negotiation skills, be considered. * Culturally appropriate care model is needed to enhance palliative and end of life care in developing countries. * A cultural care model using Leininger's Cultural Care Theory seems an appropriate path to take.
Type II cytokines direct choices of early thymic progenitor lineage and influence negative selection of myelin-reactive T cells
(2019) Gavin, Hannah; Cattin-Roy, Alexis; Zaghouani, Habib; Health Sciences Research Day (2019 : University of Missouri)
Autoimmune diseases have been known for having a strong genetic component; however, there is growing indication that shows the environment also plays an important role. One way in which the environment plays a role is though influencing central tolerance via fine tuning of the thymic microenvironment. It has been shown that early thymic progenitors (ETPs) that express the heteroreceptor (HR), which are comprised of both IL-13R[alpha]1 and IL- 4R[alpha] chain, are directed toward the myeloid lineage and serve as antigen presenting cells (APCs). Due to the role of APCs in T cell negative selection, this research looks to investigate whether type II cytokines can determine ETP lineage choice and subsequently alter negative T cell selection. --Introduction.
Treatment of hypertrophic granulation in burns : review of the literature
(2019) Linnerman, Paul; Litt, Paul; Crumley, Carolyn; Health Sciences Research Day (2019 : University of Missouri)
Introduction: Hypertrophic granulation (HG) is defined as abnormal granulation tissue, raised above the level of surrounding skin. HG often occurs with delayed healing, or in areas of graft failure in burns. HG impedes wound healing. Treatment may vary by practitioner. Includes chemical cautery with silver nitrate sticks, topical steroids, and dressing strategies.

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