Computer Science publications (MU)
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Items in this collection are the scholarly output of the Department of Computer Science faculty, staff, and students, either alone or as co-authors, and which may or may not have been published in an alternate format. Items may contain more than one file type.
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Item Computational Biology and Biomedical Informatics Expertise to Support Life and Health Sciences Research and Industry(2010-03) Shyu, Chi-Ren; University of Missouri (System); Missouri Life Sciences Summit (2010: University of Missouri--Kansas City)Interdisciplinary collaboration between computational sciences and life/health sciences is a hallmark of the MU Informatics Institute (MUII) and its new Informatics Ph.D. program. The Institute was established to foster synergy and interdisciplinary research applications in animal, plant, human health, geospatial and microbial sciences. Creative faculty and modern computation-based research facilities combine to enable groundbreaking collaborative research that relies heavily on informatics tools and expertise. In this talk, I will briefly introduce the informatics expertise of MUII core faculty in supporting experimental scientist's R&D activities with commercialization potentials by using an example scenario in personalized medicine. There are six signature research areas that are underpinning components: (1) high-throughput sequence assembly and analysis, (2) structural bioinformatics - prediction, retrievals, and interactions, (3) large-scale and high-throughput phenotype analysis, (4) data mining and knowledge discovery from large-scale omics databases and electronic health records (5) visualization and parallelism of informatics data, and (6) geospatial informatics.Item Genomic strategies for soybean oil improvement and biodiesel production(2009-04) Kumar, Rajesh; Valliyodan, Babu; Joshi, Trupti, 1977-; Xu, Dong, 1965-; Lee, Jeong; Sleper, D. A.; Hyten, David; Cregan, Perry B.; Shannon, J. Grover; Nguyen, Henry T.; Rajesh, P. N.; University of Missouri (System); Missouri Energy Summit (2009 : University of Missouri--Columbia)Soybean oil, a promising renewable energy resource, comprises 73% of biodiesel in addition to other industrial applications. Missouri is the fifth largest state in the US for soybean plantation. With the target to produce 225 million gallons of biodiesel by 2015 from the current 75 million gallons produced in 2005, efforts should not only focus on expanding the number of oil crops to meet the demand but also to increase the amount of oil per hectare for each crop. Considering the ever increasing need for biodiesel and the potential for Missouri to play a major role in national and international demand, We, at the National Center for Soybean Biotechnology focus on discovering the genetic factors that are responsible for oil content in soybean using genetic and genomic strategies. The long term goal is to apply discoveries in breeding programs and biotechnology for the development of improved soybean cultivars with increased oil content that will make this crop more competitive in end-uses. Our multidisciplinary approaches include traditional Quantitative Trait Loci (QTL) mapping, association mapping, bioinformatics and transgenics by developing new resources and utilizing already available resources such as mapping populations, diverse germplasm collections, genome sequence information and transgenes. In addition to total oil content, we are focusing on improving quality traits such as oleic acid which has direct human health benefits and application in biodiesel production. With the use of advanced genomic technologies, genetic materials, and synergistic efforts involving intra- and inter institutional collaborations, we believe that our current and future research will contribute substantially to biodiesel production. Increased production using high oil soybean cultivars will not only increase the economic gains to farmers/growers but also facilitate the US to emerge as the global leader in biodiesel production.