Search
Now showing items 81-100 of 1761
Should we stop prescribing IM progesterone to women with a history of preterm labor?
(Family Physicians Inquiries Network, 2022-01)
Q: Should we stop prescribing IM progesterone to women with a history of preterm labor? Evidence-based answer: YES, we should stop the routine prescribing of IM progesterone to prevent preterm delivery. A 2003 randomized controlled trial (RCT) found...
Management of Subclinical Hypothyroidism
(Family Physicians Inquiries Network, 2005)
function should be monitored at six- to 12-month intervals. [Strength of recommendation: C, based on expert opinion and systematic reviews with troublesome heterogeneity of disease-oriented evidence]...
When should we screen children for hyperlipidemia?
(Family Physicians Inquiries Network, 2006)
Children should be screened for hyperlipidemia when there is a history of familial hypercholesterolemia (strength of recommendation [SOR]: C). No clear evidence supports screening all children or just those with family history of cardiovascular...
Is therapy based on endoscopy results better than empiric therapy for dyspepsia?
(Family Physicians Inquiries Network, 2005)
In the initial management of dyspepsia for patients without "alarm" symptoms (weight loss, recurrent vomiting, dysphagia, anemia, evidence of bleeding, onset of dyspepsia after age 45 years), therapy based on the results of early endoscopy...
Should you consider antibiotics for exacerbations of mild COPD?
(Family Physicians Inquiries Network, 2014)
Consider antibiotics for patients with exacerbations of mild to moderate chronic obstructive pulmonary disease (COPD).
What's the most practical way to rule out adrenal insufficiency?
(Family Physicians Inquiries Network, 2009)
A morning serum cortisol level >13 mcg/dL reliably rules out adrenal insufficiency, and the test is easy and safe to perform. Because of low specificity, patients with a level of ≤13 mcg/dL need further evaluation with the cosyntropin stimulation...
What is the best test to detect herpes in skin lesions?
(Family Physicians Inquiries Network, 2006)
Polymerase chain reaction (PCR) techniques appear to be more sensitive and specific in detecting herpes simplex virus (HSV) in genital lesions (strength of recommendation [SOR]: A, based on 2 diagnostic cohort studies); however, viral culture...
What is the best initial treatment of Parkinson's disease?
(Family Physicians Inquiries Network, 2003)
with placebo, selegiline improves the motor symptoms of Parkinson's disease and allows a physician to delay the introduction of levodopa by 9 to 12 months (strength of recommendation [SOR]: A, based on randomized controlled trials). Dopamine agonists...
When is discectomy indicated for lumbar disc disease?
(Family Physicians Inquiries Network, 2011)
Emergent discectomy is indicated in the presence of cauda equina and severe, progressive neuromotor deficits (strength of recommendation [SOR]: C, expert opinion). Elective discectomy for sciatica caused by lumbar disc ...
What is the best surveillance for hepatocellular carcinoma in chronic carriers of hepatitis B?
(Family Physicians Inquiries Network, 2006)
(strength of recommendation [SOR]: B, based on a systematic review of fair-quality randomized controlled trials). It is unclear whether screening with AFP or AFP/US improves disease-specific or all-cause mortality (SOR: B)....
Exercise for the Treatment of Knee Osteoarthritis
(Family Physicians Inquiries Network, 2011)
Regular exercise reduces osteoarthritic knee pain and improves functioning. (Strength of Recommendation: A, based on systematic reviews.) Aerobic and strength-training exercises, including land- and water-based exercises, are effective for treating...
Chronic gastritis
(Family Physicians Inquiries Network, 2010)
This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of chronic gastritis.
Are steroid injections effective for tenosynovitis of the hand?
(Family Physicians Inquiries Network, 2007)
Yes. Steroid injections are an effective first-line therapy for flexor tenosynovitis of the hand, with a number needed to treat [NNT] of 2.3 for injection of steroids and lidocaine (strength of recommendation [SOR]: B, based on 1 prospective RCT...
Management of ADHD in preschool-aged children
(Family Physicians Inquiries Network, 2013)
RCTs.) Alternative therapies, such as elimination diets, have limited evidence of success and should generally be avoided or used in conjunction with standard therapies. (SOR: B, based on a systematic review of a small number of heterogeneous RCTs.)...
What is the most effective beta-blocker for heart failure?
(Family Physicians Inquiries Network, 2003)
of recommendation [SOR]: A, based on large randomized placebo-controlled trials). No differences in mortality or patient tolerance have been demonstrated in studies comparing carvedilol and metoprolol (SOR: B, based on small head-to-head trials)....
Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
(Family Physicians Inquiries Network, 2022-07)
Q: Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression? Evidence-based answer: YES. Augmentation with second-generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective...
Do oral contraceptives carry a significant risk of stroke for women with migranes?
(Family Physicians Inquiries Network, 2013)
Evidence-based answer: Estrogen-containing oral contraceptives may raise the risk of ischemic stroke in women with migraine, particularly migraine with aura (strength of recommendation [SOR]: C, small case-control studies with methodological flaws...
Can we prevent splenic rupture for patients with infectious mononucleosis?
(Family Physicians Inquiries Network, 2005)
-control study). Clinical evidence indicates that most splenic ruptures occur within 4 weeks of symptom onset, which correlates with ultrasound data showing resolution of splenomegaly by 30 days from symptom onset (SOR: B, case-control study). Given the morbidity...
Intranasal steroids vs antihistamines: which is better for seasonal allergies and conjunctivitis?
(Family Physicians Inquiries Network, 2012)
Intranasal steroids provide better relief for adult sufferers, according to nonstandardized, nonclinically validated scales. Steroids reduce subjective total nasal symptom scores (TNSS)--representing sneezing, itching, ...
Are breast self-exams or clinical exams effective for screening breast cancer?
(Family Physicians Inquiries Network, 2005)
Breast self-examination has little or no impact on breast cancer mortality and cannot be recommended for cancer screening (strength of recommendation [SOR]: A, based on a systematic review of high-quality randomized, controlled trials [RCTs...