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Now showing items 41-60 of 414
Studying physician use and satisfaction with web-based treatment guides that incorporate patient information from the electronic medical record [abstract]
(2010-03)
Clinical decision support tools are important components of the electronic medical record. Previous studies have demonstrated that such tools can directly improve patient care outcomes and the performance of healthcare ...
Shock Wave Based Cell Transfection and Fluorescent Organosilicate Nanoparticles for Targeted Drug Delivery [abstract]
(2010)
Nanotechnology is a multidisciplinary field that has applications in life sciences, alternative energy, national defense, and electronics. In the field of medicine, nanotechnology may enable intelligent drug delivery using ...
In vivo and in vitro evaluation of MRI contrast agent targeting human prostate cancer [abstract]
(2010-03)
Prostate cancer is the most common cancer for men in the US, affecting 1 in 6 men. Noninvasive imaging techniques have played important roles in prostate cancer staging and treatment planning. In particular, diffusion-weighted ...
Dangerous Drug Reactions on the S&A iPhone App [abstract]
(2010)
The S&A drug database for handhelds, sold to dermatologists for 8 years, was uploaded as a new iPhone application (app), February 2010. Our program notes all warnings at the several FDA levels: boxed warnings, bold warnings, ...
In vivo and in vitro evaluation of 64 CU-labeled bombesin analogs for targeting gastrin-releasing peptide receptors on human prostate cancer [abstract]
(2010-03)
Introduction: Gastrin-releasing peptide receptors (GRPr) are expressed in high numbers on human prostate cancer. The bombesin peptide derivative, BBN(7- 14)NH2, has high affinity and selectivity to GRPr. Therefore, Copper-64 ...
Intrathecal baclofen as a pharmacologic treatment for tactile defensiveness and symptoms of autism spectrum disorder [abstract]
(2010-03)
Patient: An 18-year-old male with Autism Spectrum Disorder (ASD) and Tactile Defensiveness suffered a traumatic brain injury (TBI). Case Description: Pre-TBI, the patient exhibited mild tactile defensiveness but was ...
A Comparative Study between Antibody and Peptide Conjugated Gold Nanoparticles for In Vivo Targeting of EGFR in Pancreatic Cancer Bearing Mice Models [abstract]
(2010-03)
Pancreatic cancer is the fourth leading cause of cancer related deaths in the United States due to its severe aggressiveness and lethal malignancy. Epidermal Growth Factor Receptor (EGFR) is over expressed in more than 95% ...
Role of natural and synthetic progestins in progression of human breast cancer cells in an animal model [abstract]
(2010-03)
Post-menopausal women with an intact uterus receive combined dose of estrogen and progestin during hormone replacement therapy (HRT) to reduce clinical symptoms such as hot flashes. Progestins, which include natural and ...
Disruption of e-cadherin junctional integrity in ovarian cancer cells is promoted by LPA-induced MMP-9 activity [abstract]
(2010-02)
Approximately 22,000 U.S. women are newly diagnosed each year with epithelial ovarian cancer (EOC), 75% of whom present with existing metastases and peritoneal ascites. A key event in EOC metastasis is disruption of cell-cell ...
Brain Science and Living Neuronal Networks for Smart Grids [abstract]
(2010)
The objective of this multi-disciplinary collaborative research is to infuse more neurobiology into control systems, to make them more brain-like and better able to carry out real-time control of complex systems. This ...
Discovery and Mechanistic Characterization of Novel SARS Coronavirus Inhibitors that Block Viral Entry [abstract]
(2010-03)
Severe acute respiratory syndrome (SARS) is an infectious and highly contagious disease that is caused by SARS-associated coronavirus (SARS-CoV). Viral entry is a key target step for therapies because it can prevent the ...
Early Breast Cancer Detection Using Fluorescence Mediated Tomographic Imaging [abstract]
(2010)
Development of reliable technologies for early detection and screening of breast cancer is significant since the overall accuracy of traditional mammography remains low for diagnosis of benign and malignant lesions. In ...
Gold nanoparticles (GNP) or adeno-associated virus (AAV) mediated gene delivery in human corneal endothelial cells [abstract]
(2010-03)
Purpose: Healthy Corneal endothelium is essential for corneal clarity. Treatment of defective corneal endothelial function often requires corneal transplant. Gene therapy is an attractive approach to treat/cure corneal ...
Lawnmower injuries : avoidable morbidity/mortality? [abstract]
(2010-03)
Background: Lawnmower injuries are common around the world. We analyze our institution's experience, discuss the societal impact, and review management and prevention strategies. Methods: A fifteen- year retrospective ...
Science Outreach and Informal Science Education-Programs and Partnerships [abstract]
(2010-02)
Our vision is to create a culture where engagement between scientists and the public is the norm. This will contribute to workforce development, public understanding of science and its economic impacts in our state. We are ...
Pancreatic islet transplantation to treat diabetes - defining molecular tools to select suitable islets [abstract]
(2010)
A complete understanding of pancreatic islet biology is essential to the development of preventive or curative interventions for diabetes. It has been known that subpopulations of islets of different sizes exist; however, ...
Local ethanol promotes extracellular accumulation of adenosine in the orexinergic perifornical hypothalamus [abstract]
(2010-03)
Ethanol promotes sleep. However, the neuroanatomical site where ethanol acts to modulate sleep/wakefulness is unknown. The perifornical hypothalamus (PFH) contains wake-promoting orexinergic neurons. Studies from our ...
Interpreting the origins of the human hip : Evaluation of articular contact area in the ancestral hip joint [abstract]
(2010-03)
Understanding hip joint functional anatomy is critical to interpreting the origins of the human hip. A new pelvis of the 9 million year old ape Rudapithecus, argued to represent a close African ape-human relative, provides ...
Porcine induced pluripotent stem cells (piPSC) for expanding the use of swine in biomedical research
(2010-03)
Our goal is to create porcine pluripotent stem cells, i.e. ones capable of differentiating into all cell types of the body that can expand the use of swine as a biomedical model for studying human disease. It is well ...
In vitro study of effect of light dose and photofin concentration on photodynamic therapy of medulloblastoma cells [abstract]
(2010-03)
This study was aimed at investigating two variables in the photodynamic therapy (PDT) of medulloblastoma cells: light dose and Photofrin concentration. To investigate the effect of Photofrin concentration, a Daoy medulloblastoma ...