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Characterization of interleukin-1 beta 2, a novel interleukin-1 expressed by the early pig conceptus during establishment of pregnancy
(University of Missouri--Columbia, 2014)
It is essential that the early mammalian embryo attaches to the uterus or implants to survive. Most embryonic mortality is associated with complications during this process resulting in a loss of 25-60% of embryos or ...
Effect of RU486, a progesterone antagonist, on uterine progesterone receptor, embryonic development and ovarian function during early pregnancy in pigs
(University of Missouri--Columbia, 2009)
Progesterone (P4) down-regulates the progesterone receptor (PGR) exclusively within the epithelium of the pig uterus near d 8 of the estrous cycle and pregnancy. How P4 down-regulates the PGR is not understood but is ...
New perspective on the role of conceptus estrogens in conceptus development, maternal recognition, and the establishment of pregnancy in pigs.
(University of Missouri--Columbia, 2018)
The proposed signal for maternal recognition of pregnancy in pigs is estrogen, produced by the elongating conceptus. To understand the role of estrogen in porcine conceptus elongation and pregnancy establishment, a loss ...
Ablation of conceptus PTGS2 provides a new understanding of early pregnancy events in the pig
(University of Missouri--Columbia, 2019)
Pig conceptuses produce and secrete estrogens (E[2]), interleukin 1 beta 2 (IL1B2), and prostaglandins (PGs) during the period of rapid trophoblast elongation and establishment of pregnancy. Previous studies established ...