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Development of an in-vitro model of equine corneal wound healing : pharmacologic and gene therapy modalities in the reduction of corneal fibrosis
(University of Missouri--Columbia, 2010)
Objective: To establish an in vitro model for the investigation of equine corneal wound healing. To accomplish this goal, a protocol to isolate and culture equine corneal keratocytes, fibroblasts and myofibroblasts was ...
Acute phase proteins in naturally occurring respiratory disease of feedlot cattle : a novel approach to diagnosisAcute phase proteins in naturally occurring respiratory disease of feedlot cattle : a novel approach to diagnosis
(University of Missouri--Columbia, 2014)
Bovine respiratory disease (BRD) is the most costly disease of feedlot cattle in the United States. Costs associated with BRD have been estimated from $13.90 to $15.57 per head with annual losses to the cattle industry ...
Evaluation of autoimmune disease as a risk factor for lymphoma
(University of Missouri--Columbia, 2013)
The immune system has an intricate relationship with cancer. It is responsible for the prevention, management, and resolution of cancer. In people and dogs autoimmune diseases have been linked to hematopoietic neoplasia. ...
Longitudinal evaluation of effects of adipose-derived mesenchymal stem cells in a model of feline allergic asthma
(University of Missouri--Columbia, 2014)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Asthma is characterized by airway inflammation, airway hyperresponsiveness (AHR), and structural changes in the lungs. Mesenchymal stem cells (MSCs) ...
Canine T-regulatory cells in aging and cancer : quantifying a unique T cell subset
(University of Missouri--Columbia, 2010)
T regulatory lymphocytes (Tregs), identified by the markers CD4, CD25, and FoxP3, are an essential part of the immune system and promote tolerance with the purpose of minimizing auto-immune disease. However, if Tregs are ...
The use of sodium iodide for the management of bovine respiratory disease
(University of Missouri--Columbia, 2017)
Objective: The purpose of these studies was to (1) determine the effect of a single dose of oral sodium iodide on weaned beef calves and (2) determine the outcome of clinical application of a single dose of oral sodium ...
Therapeutic potential of the anti-fibrotic drug Suberanilohydroxamic acid (SAHA) in canine corneal fibrosis
(University of Missouri--Columbia, 2016)
Purpose: The aims were to (1) investigate the molecular mechanisms mediating the antifibrotic effect of SAHA in the canine cornea using an in vitro model and (2) to develop a novel in vivo model of corneal fibrosis in dogs ...
Angular limb deformities affecting the canine radius and ulna : classification using the center of rotation of angulation method
(University of Missouri--Columbia, 2015)
We hypothesized that 1) antebrachial ALDs would be more complex with respect to multiplicity in chondrodystrophic dogs, and 2) more complex ALDs would exhibit a higher incidence of concurrent joint radiographic disease. ...
In vitro and ex vivo therapeutic strategies for equine corneal fibrosis
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Purpose: The aims were to (1) To explore the impact of equine corneal fibroblast (ECF) to myofibroblast (ECM) differentiation by altering the expression ...
The use of ventilator-acquired pulmonary mechanics and computed tomography in the assessment of interventions for experimental feline asthma
(University of Missouri--Columbia, 2016)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] In an experimental model of feline asthma, computed tomography (CT) and ventilator-acquired pulmonary mechanics were used in the assessment of various ...
Analysis of platlet function in the setting of controlled trauma in dogs using a whole blood electrical impedance platelet aggregometer
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Post-traumatic hemorrhage remains one of the leading causes of human deaths, accounting for 30 to 56 percent of pre-hospital post-traumatic deaths. ...