Search
Now showing items 1-6 of 6
Examination of biological factors that mediate the influence of physical activity on palatability driven feeding
(University of Missouri--Columbia, 2019)
factors between subjects such as sex or genetics may influence this interaction. The experiments presented in this dissertation utilize unique models applying systems and behavioral neuroscience approaches to test the hypothesis that differences...
Organization of brain and spinal cord locomotor networks in larval lamprey
(University of Missouri--Columbia, 2006)
In vertebrates, brain locomotor command systems activate spinal central pattern generators (CPGs) to initiate locomotor behavior. The size and pharmacology of brain command systems are unknown, and the movements that result ...
Real-time detection of dopamine -- aptamer interactions in a nanopore: a label-free toolkit for study of nucleic-acid-based molecular sensors.
(University of Missouri--Columbia, 2021)
Understanding how small molecules regulate nucleic acid structures is important in both biomechanism elucidation and biotechnological applications. Through the conformational variation, native nucleic acid motifs can be ...
Impact of the NAD+ salvage pathway on the motor system and bioenergetics
(University of Missouri--Columbia, 2023)
Nicotinamide adenine dinucleotide (NAD+) is a metabolite pivotal to numerous cellular functions, including energy metabolism, DNA repair, and protein modification. The majority of NAD+ is generated by the NAD+ salvage ...
Low-intensity blast-induced mild traumatic brain injury : linking blast physics to biological outcomes
(University of Missouri--Columbia, 2019)
Blast-induced mild traumatic brain injury (mTBI) is of particular concern among military personnel due to exposure to blast energy during military training and combat. The impact of primary low-intensity blast (LIB) mediated ...
Disease characterization and pre-clinical testing in canine models of the neuronal ceroid lipofuscinoses
(University of Missouri--Columbia, 2021)
The neuronal ceroid lipofuscinoses (NCLs) are inherited lysosomal storage disorders characterized by intracellular accumulation of autofluorescent storage material and by progressive degeneration of neurons in the brain ...