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Viral envelope proteins and the HIV-1 accessory gene Vpu mediate selectivity of viral and host proteins in retroviral assembly
(University of Missouri--Columbia, 2012)
, where an HIV-1 accessory gene known as Vpu restricts the envelope protein from gibbon ape leukemia virus (GaLV Env) from assembling with HIV-1. Further studies from our lab demonstrated that Vpu recognizes GaLV Env in a manner almost identical to CD4...
Comparative study of Human Immunodeficiency Virus type 1 and type 2 single and dual infections
(University of Missouri--Columbia, 2020)
Human Immunodeficiency Virus (HIV) type 1 and type 2 are two related lentiviruses that have strikingly divergent features in terms of transmission rates, distribution, pathogenesis, and clinical outcomes. In places where ...