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HIV-1 5'UTR RNA structures: connections to infectious lifecycle and potential therapeutic applications
(University of Missouri--Columbia, 2021)
for treatment. This dissertation presents work utilizing a wide range of biochemical approaches to explore the importance of the HIV-1 5'untranslated region (5'UTR) RNA in infection and strategies utilizing this gained knowledge for screening of novel...
RNA structural studies : implications in HIV-1 replication and the origins of life
(University of Missouri--Columbia, 2021)
Structure and function relationships are important to understand many biological processes. Biological components are not one dimensional and their structures may drive key aspects of their function. This dissertation focuses on understanding key...