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Duchenne muscular dystrophy gene therapy in the canine model
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Duchenne muscular dystrophy (DMD) is a devastating muscle wasting disease caused by loss of function mutations in the dystrophin gene, resulting in the ...
Four-limb IMU sensors for canine gait analysis
(University of Missouri--Columbia, 2019)
of our method, we conducted synchronized gait tests with the GAIT4Dog, a commercially available system. Our algorithm detected the swing start event in both front and hind limbs with high accuracy with a mean error [plus-minus] standard deviation of 0...
Reparative dysfunction during muscle regeneration in Duchenne muscular dystrophy: therapeutic approaches to modulating the muscle environment and muscle stem cells
(University of Missouri--Columbia, 2019)
the environment by improving fibrosis, stiffness, and fiber orientation, which significantly improved early muscle regeneration but not late regeneration (2 [greater than] and [less than] 4 months post-transplant) via enhancing muscle stem cells differentiation...