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Computational studies of three chemical systems
(University of Missouri--Columbia, 2011)
is the study of pyrogallol[4]arene with R-groups R=H and R=phenyl. This macrocycle self-assembles into dimeric and hexameric nanocapsules. Several different structures for the macrocycle and its subunits, their relative energies, and their solvent interactions...
Investigating the bifunctional chelate approach for radiopharmaceutical development
(University of Missouri--Columbia, 2010)
for in vivo imaging of GRP receptor positive tumors. A series of peptides that differed in their C-terminal ends or 6th position amino acid, were synthesized and coupled to the chelate, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA...
Radionuclide production and separation techniques for radiopharmaceutical development and nuclear waste processing
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] With increasing cancer incident rates and advancements in nuclear medicine, the demand for optimizing pathways to produce radionuclides or investigating ...
Characterizing and understanding self-assembling, nanocapsule host-guest systems
(University of Missouri--Columbia, 2010)
Supramolecular, self-assembled nanocapsules have been shown to be capable of entrapping fluorescent guests. Previous solid- and solution-state research, focusing on hydrogen-bonded C-alkylpyrogallol[4]arenes (PgC6)nanocapsules, have shed light...