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Development of translational models for intervertebral disc degeneration using a comparative approach for canine and human patients
(University of Missouri--Columbia, 2020)
-chondrodystrophic (NCD) breeds of dogs show different phenotypes of IVDD, each of which mimic phenotypes described for human patients. The main goal for this PhD research was to develop and validate canine models for human IVDD with a focus on distinguishing molecular...
Pass the salt : elucidating the chondroprotective properties of hyperosmolar saline irrigation solutions
(University of Missouri--Columbia, 2023)
(Chapters 1 & 2) provides a compressive introduction and literature review of the synovial joint, and the history, advances, and limitations of arthroscopic surgery. Chapter 3 examines the differences in pro-inflammatory and degradative mediator production...