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Synthesis, self-assembly and applications of tribenzopenta-phene derivatives and triphenylene-based conjugated foldamers
(2013)
and polymers which can self-organize into a helical conformation have been extensively studied. Such studies have not only led to much better understanding of the principles behind noncovalent folding, but also brought about a number of exciting applications...
Effects of Selected Contaminants on the Physical, Chemical, and Geotechnical Properties of Aquifer Solid
(2014)
contaminants on the hydraulic conductivity of sand. Bulk sand samples from the Missouri River Valley aquifer— a major source of groundwater supply in the U.S. Midwest— were collected for this study. Sand samples, representing the aquifer and vadose zone...
Raman, Infrared and Microwave Spectra, Conformational Stability, R₀ Structural Parameters and Vibrational Assignments of Some Organoamines, Organophosphines, Alcohols And Substituted Four And Five Membered Rings
(2014)
The infrared and Raman spectra of compounds with amino, phosphours, silane and hydroxyl functional groups, as well as some with cyclic skeletal structures have been recorded of the gas and in condensed phases. Temperature ...
Development of Random Triblock Copolymer Based Nanoparticulate Formulation for Sustained Release of Macromolecules/Biologics in Treatment of Posterior Segment Ocular Diseases
(University of Missouri -- Kansas City, 2018)
Random triblock copolymers (RTB) were successfully synthesized by ring opening
copolymerization method. RTB copolymers are composed of FDA approved materials such as
polyethylene glycol (PEG), glycolide (GA), lactide ...
Design, synthesis and evaluation of novel intercalator analogs targeting therapeutically important polymerases and folded RNA
(2013)
Polymerases and ribonucleic acids have been found to play major roles in the
causation and progression of several diseases. Targeting such important therapeutic targets
using small molecules can help achieve their specific ...
Development of Closomer And MIBG based Nanoformulation: Application to HIV Prevention and Neuroblastoma Therapy
(2023)
are summarized in Chapters 4-5 and 6, respectively. In Chapters 1 and 2, an overview of the aims and scope of this study, and a literature review of the two parts of this dissertation is extensively discussed. In Chapter 3, it was hypothesized that fluorine 19...
Ritonavir - A Novel Multidrug Resistance Modulator in Cancer Chemotherapy and Ocular Neovascular Diseases
(2014-08-28)
Multidrug resistance (MDR), a clinical outcome characterized by subtherapeutic
intracellular drug concentration, is one of the predominant factors limiting effective cancer
chemotherapy. Several possible mechanisms and ...