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Does evidence support the use of supplements to aid in BP control?
(Family Physicians Inquiries Network, 2020)
Q: Does evidence support the use of supplements to aid in BP control? Evidence-based answer: Yes. A number of well-tolerated natural therapies have been shown to reduce systolic and diastolic blood pressure (BP). (See TABLE1-8 for summary.) However...
Time to conception after miscarriage : how long to wait?
(Family Physicians Inquiries Network, 2019)
Q: Time to conception after miscarriage: how long to wait? Evidence-based answer: an interpregnancy interval (IPI) of < 6 months following miscarriage is associated with an increased live birth rate in subsequent pregnancy, lower risks of preterm...
Is therapy based on endoscopy results better than empiric therapy for dyspepsia?
(Family Physicians Inquiries Network, 2005)
In the initial management of dyspepsia for patients without "alarm" symptoms (weight loss, recurrent vomiting, dysphagia, anemia, evidence of bleeding, onset of dyspepsia after age 45 years), therapy based on the results of early endoscopy...
What's the best test for underlying osteomyelitis in patients with diabetic foot ulcers?
(Family Physicians Inquiries Network, 2015)
, evidence-based guidelines)....
What are the treatment options for SSRI-related sexual dysfunction?
(Family Physicians Inquiries Network, 2002)
Substituting bupropion, nefazodone, or mirtazapine is beneficial. (Grade of recommendation: B, randomized controlled trials [RCTs].) Augmentation therapy with amantadine, bupropion, and buspirone is no better than placebo. ...
Suctioning neonates at birth: time to change our approach
(Family Physicians Inquiries Network, 2014)
There's a better way to clear secretions from a neonate's mouth and nose, and it's less likely to cause adverse effects. Practice Changer: Stop suctioning neonates at birth. There is no benefit to this practice, and it can cause bradycardia...
What is the best nonsurgical therapy for pelvic organ prolapse?
(Family Physicians Inquiries Network, 2014)
Q. What is the best nonsurgical therapy for pelvic organ prolapse? Evidence-based answer: Pelvic floor muscle training (PFMT) and pessaries are equally effective in treating symptoms of pelvic organ prolapse (POP). PFMT transiently improves patient...
The shrinking case for saw palmetto
(Family Physicians Inquiries Network, 2012)
Advise men with benign prostatic hyperplasia (BPH) not to take saw palmetto for urinary symptoms. Explain that it has not been found to alleviate symptoms, even at triple the standard dose. Stength of recommendation: A: Based on evidence from a high...
Patients insist on antibiotics for sinusitis? Here is a good reason to say no
(Family Physicians Inquiries Network, 2008)
and create unnecessary expense. Stength of recommendation: A: Based on a meta-analysis of 9 randomized trials in primary care practice....
Prophylactic oxytocin: Before or after placental delivery?
(Family Physicians Inquiries Network, 2008)
Timing alone doesn't influence the drug's efficacy in preventing postpartum bleeding (strength of recommendation: B, randomized controlled trial [RCT] and prospective cohort studies).
Does moderate exercise prevent MI for patients with coronary heart disease?
(Family Physicians Inquiries Network, 2004)
Moderate exercise reduces mortality for patients with known coronary heart disease but does not significantly decrease the risk of recurrent nonfatal myocardial infarction (MI) (strength of recommendation [SOR]: A, based on systematic review...
Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression?
(Family Physicians Inquiries Network, 2022-07)
Q: Are antipsychotics effective adjunctive Tx for patients with moderate-to-severe depression? Evidence-based answer: YES. Augmentation with second-generation antipsychotics, especially aripiprazole and quetiapine, appears to be effective...
Do patients with type 2 diabetes who aren't taking insulin benefit from self-monitoring blood glucose?
(Family Physicians Inquiries Network, 2013)
-oriented evidence). More frequent SMBG--4 to 7 times weekly--doesn't reduce HbA1c more than less frequent self-monitoring--1 or 2 times a week (SOR: B, a systematic review and meta-analysis of disease-oriented evidence)....
For fibromyalgia, which treatments are the most effective?
(Family Physicians Inquiries Network, 2005)
well-being and have a moderate beneficial effect on tenderness and stiffness (strength of recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs]). Selective serotonin reuptake inhibitors (SSRIs) may moderately...
How safe and effective is ondansetron for nausea and vomiting in pregnancy?
(Family Physicians Inquiries Network, 2019)
Q: How safe and effective is ondansetron for nausea and vomiting in pregnancy? Evidence-based answer: oral ondansetron is more effective than a combination of pyridoxine and doxylamine for outpatient treatment of nausea and vomiting in pregnancy...
PEDs tuberculosis
(Family Physicians Inquiries Network, 2010)
This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of tuberculosis in children.
Which smoking cessation interventions work best?
(Family Physicians Inquiries Network, 2011)
Nicotine replacement therapy (NRT), bupropion, nortriptyline, clonidine, and varenicline are all effective, although insufficient evidence exists to recommend one intervention over another (SOR: A, systematic reviews). Effective nonpharmacologic...
Which oral nonopioid agents are most effective for OA pain?
(Family Physicians Inquiries Network, 2019)
Q Which oral nonopioid agents are most effective for OA pain? Evidence-based answer: nonsteroidal anti-inflammatory drugs (nsaids), when used at the maximum clinically effective dose, reduce osteoarthritis (OA) pain in large joints more effectively...
Glycemic Control in Patients with Type 2 Diabetes
(Family Physicians Inquiries Network, 2007)
There is no clearly superior oral agent for glycemic control in patients with type 2 diabetes. (Strength of Recommendation [SOR]: C) Metformin (Glucophage) has shown additional benefit when compared with other treatments ...
What risk factors contribute to C difficile diarrhea?
(Family Physicians Inquiries Network, 2011)
Certain antibiotics and using 3 or more antibiotics at one time are associated with Clostridium difficile-associated diarrhea (CDAD) (strength of recommendation [SOR]: B, 1 heterogeneous systematic review and several ...