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New perspective on the role of conceptus estrogens in conceptus development, maternal recognition, and the establishment of pregnancy in pigs.
(University of Missouri--Columbia, 2018)
The proposed signal for maternal recognition of pregnancy in pigs is estrogen, produced by the elongating conceptus. To understand the role of estrogen in porcine conceptus elongation and pregnancy establishment, a loss ...
Ablation of conceptus PTGS2 provides a new understanding of early pregnancy events in the pig
(University of Missouri--Columbia, 2019)
Pig conceptuses produce and secrete estrogens (E[2]), interleukin 1 beta 2 (IL1B2), and prostaglandins (PGs) during the period of rapid trophoblast elongation and establishment of pregnancy. Previous studies established that IL1B2 is essential...
Effect of RU486, a progesterone antagonist, on uterine progesterone receptor, embryonic development and ovarian function during early pregnancy in pigs
(University of Missouri--Columbia, 2009)
for establishment of pregnancy. Progesterone is suggested to increase expression of a cytokine, RANKL, in the uterine epithelium that can activate nuclear factor-kappa B (NF-[kappa]B). Nuclear factor-kappa B is a transcription factor thought to block expression...