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The role of load in initiation and progression of cartilage pathology
(University of Missouri--Columbia, 2007)
Articular cartilage is primarily responsible for dissipation of load in diarthrodial joints. Load plays a critical role in maintaining cartilage health, but can also be a primary contributing factor in cartilage disease ...
Development of a post-traumatic osteoarthritis model to evaluate the effects of impact velocity and maximum strain on articular cartilage cell viability, matrix biomarkers, and material properties
(University of Missouri--Columbia, 2009)
Post-traumatic osteoarthritis (PTOA) is a very painful and debilitating disease that is associated with mechanical injury to articular cartilage, yet the severity of trauma required to induce it is unknown. The objective ...
Development of post-traumatic osteoarthritis models to evaluate the effects of impact injury on joint health for clinical disease treatment and prevention
(University of Missouri--Columbia, 2013)
Osteoarthritis is one of the most common, debilitating, musculoskeletal diseases in the world. Currently, there is no cure. It is well-known that a traumatic, joint injury increases the risk of developing post-traumatic ...