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Accelerating data-driven discover in type 1 diabetes: an informatics-based approach
(University of Missouri--Columbia, 2022)
Type 1 diabetes (T1D) is a lifelong chronic disease characterized by the absolute or near-absolute loss of insulin. For affected individuals, management of T1D is an unremitting challenge that involves constant blood glucose ...
Identification of immune-related gene signatures to evaluate immunotherapeutic response in cancer patients using exploratory subgroup discovery
(University of Missouri--Columbia, 2022)
Phenotypic and genotypic heterogeneity are characteristic features of cancer patients. To tackle patients[trademark] heterogeneity, immune checkpoint inhibitors (ICIs) represent one of the most promising therapeutic ...