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Development of translational models for intervertebral disc degeneration using a comparative approach for canine and human patients
(University of Missouri--Columbia, 2020)
Intervertebral discs (IVDs) are unique musculoskeletal tissues within functional spinal unit organs comprising the spinal column that distribute loads and allow complex movements for vertebrates. IVD degeneration has been ...
Pathobiological analysis of developmental dysplasia of the hip and its progression to osteoarthritis
(University of Missouri--Columbia, 2022)
Developmental dysplasia of the hip (DDH) is recognized as one of the leading causes of early-onset hip osteoarthritis and a primary reason for undergoing total hip arthroplasty prior to 50 years of age. Even with an increase ...
Biological responses of ligament and tendon graft-derived fibroblasts to clinical levels of cyclic strain
(University of Missouri--Columbia, 2020)
Anterior Cruciate Ligament (ACL) is one of the major ligaments in the knee. ACL injury is the partial or complete tear of the ACL usually as a consequence of a traumatic sports related injury. ACL injury commonly affects ...
Patient adherence to orthopaedic treatment plans : toward patient-centered definitions, measurement, and management
(University of Missouri--Columbia, 2023)
[EMBARGOED UNTIL 5/1/2024] Patient adherence to prescribed management protocols is associated with improved function, higher patient satisfaction, and lower complication rates following orthopaedic treatments. While adherence ...