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Reflux, aspiration and respiratory disease in dogs : clinical consideration and advances in aerodigestive diagnostics
(University of Missouri--Columbia, 2019)
The aspiration of gastric contents into the respiratory tract has been associated with the development and progression of multiple respiratory diseases in humans. In veterinary medicine the term "aspiration" is considered synonymous with "aspiration...
Biological responses of ligament and tendon graft-derived fibroblasts to clinical levels of cyclic strain
(University of Missouri--Columbia, 2020)
Anterior Cruciate Ligament (ACL) is one of the major ligaments in the knee. ACL injury is the partial or complete tear of the ACL usually as a consequence of a traumatic sports related injury. ACL injury commonly affects ...
Improving ligament tissue scaffold with the use of genipin and gold nanoparticles
(University of Missouri--Columbia, 2020)
Decellularized tissue is used for a wide array of tissue injuries with tendon and ligament repair being among the most common. However, despite their frequent use there is concern over the lengthy inflammatory period and ...
Defining recurrent laryngeal nerve injury in a mouse model for regenerative therapeutic investigations
(University of Missouri--Columbia, 2019)
Injury of the recurrent laryngeal nerve (RLN), a branch of the vagus nerve, results in ipsilateral vocal fold (VF) paralysis that contributes to dysphagia, dysphonia, and dyspnea (i.e., swallow, vocal, and respiratory ...
The respiratory microbiota of dogs and cats in health and disease: expanding our breadth of knowledge
(University of Missouri--Columbia, 2022)
, studies in these species have the potential to advance human and veterinary medicine, alike. 16S rRNA amplicon sequencing of DNA was extracted from bronchoalveolar lavage fluid as well as rectal, oropharyngeal, and blood samples when available from healthy...
The use of massively parallel sequencing to study the virome, epigenome and genome of canine and feline cancers
(University of Missouri--Columbia, 2019)
inhibitors and targeted immunotherapy. Veterinary oncology has been slow to enter the field of genome-wide studies, largely due to costs. Five years ago, the first whole genome of a canine cancer patient was published. Because of NIH support and the steady...
Interference with biologic transmission of Anaplasma marginale by targeting the tick-pathogen interface
(University of Missouri--Columbia, 2022)
, increasing tick populations, emerging tick-borne pathogens and continued challenges of achieving effective and sustained tick control, ticks and tick-borne diseases have increased in importance from medical and veterinary public health perspectives. Host...
Epidemiology of non-aureus staphylococcal mastitis in dairy goats
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The hypothesis of this work was that molecular-based speciation and strain-typing methods would help differentiate staphylococcal species with greater ...
Avian [beta]-defensins as antimicrobial and immunomodulatory agents
(University of Missouri--Columbia, 2018)
The increasing prevalence of antibiotic-resistance and lack of effective antibiotics pose a serious threat to animal health and public health. Host antimicrobial peptides (AMPs) show broad-spectrum antimicrobial activity against various microbes...
Characterization of the rat Atg16l1 gene and its role in autophagy and disease
(University of Missouri--Columbia, 2020)
Crohn's disease (CD) is a potentially life-threatening inflammatory condition of the gastrointestinal tract affecting approximately 1.6 million Americans. Previous studies confirm the important role of genetics in IBD. ...
Morphological and biomechanical predictions of cranial kinesis in reptile evolution
(University of Missouri--Columbia, 2019)
Feeding is a complex behavior that all tetrapods engage in on a regular basis to procure energy and survive. The reptilian feeding apparatus includes many types of feeding behaviors including multiple methods of engaging ...
Function and evolution of the crocodyliform feeding apparatus
(University of Missouri--Columbia, 2021)
The evolution of crocodylians from their suchian ancestors represents one of the great transformations in vertebrate evolution. Modern crocodylians have flat skulls and generate high forces during feeding, but crocodylian ...