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A unified phylogeny-based nomenclature for histone variants
(2012-05-31)
AbstractHistone variants are non-allelic protein isoforms that play key roles in diversifying chromatin structure. The known number of such variants has greatly increased in recent years, but the lack of naming conventions ...
Involvement of metabotropic glutamate receptor 5, AKT/PI3K Signaling and NF-kappaB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes
(2012-03-15)
Abstract
Methamphetamine (MA) is one of the commonly used illicit drugs and the central nervous system toxicity of MA is well documented. The mechanisms contributing to this toxicity have not been fully elucidated. In this ...
Motivational Interviewing for encouraging quit attempts among unmotivated smokers: Study protocol of a randomized, controlled, efficacy trial.
(2012-06-19)
Abstract
Background
Although the current Clinical Practice Guideline recommend Motivational Interviewing for use with smokers not ready to quit, the strength of evidence for its use is rated ...
ART adherence changes among patients in community substance use treatment: a preliminary analysis from MACH14
(2012-10-11)
Abstract
Background
Opiate substitution treatment has been associated with better adherence to lifesaving antiretroviral medications, but the impact of other substance abuse treatment on ...
RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis
(2012-12-21)
Abstract
Background
Rheumatoid arthritis (RA) is a chronic autoimmune-disease of unknown origin that primarily affects the joints and ultimately leads to their destruction. Growing evidence ...
Perceptions of neighborhood social environment and drug dependence among incarcerated women and men: a cross-sectional analysis
(2012-09-10)
Abstract
Background
Perception of neighborhood social environment can influence an individual’s susceptibility to drug dependence. However, this has never been examined with a jailed ...
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor
(2012-06-14)
Abstract
Background: Altered immune function during ageing results in increased production of nitric oxide (NO) and other inflammatory mediators. Recently, we have reported that NO production was inhibited ...
Insights into the pathogenesis of axial spondyloarthropathy from network and pathway analysis
(2012-07-16)
Abstract
Background
Complex chronic diseases are usually not caused by changes in a single causal gene but by an unbalanced regulating ...