Browsing by Title "Formation and properties of endogenous adducts and crosslinks generated by amine-catalyzed strand cleavage at an AP site in duplex DNA"
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Formation and properties of endogenous adducts and crosslinks generated by amine-catalyzed strand cleavage at an AP site in duplex DNA
(University of Missouri--Columbia, 2022)Abasic sites in DNA are a very common lesion. They are formed spontaneously and in the presence of biological amines, enzymes, and proteins. If unrepaired, abasic sites lead to DNA strand breaks and crosslinks. This thesis ...