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Studies on the development of a bacillus endospore-based microparticle vaccine platform
(University of Missouri--Columbia, 2011)
The rapid and safe immunization of populations is critical in response to emerging infectious diseases or biological attacks. Currently, many subunit vaccines are insufficiently immunogenic to protect against pathogen ...
Regulating the regulators : using CD25 depletion to enhance immune responses to a model plasmid-based vaccine
(University of Missouri--Columbia, 2008)
Due to their ease of production and safety, plasmid-based vaccines have become prime candidates for both prophylactic and therapeutic human vaccination. In experimental animal models, vaccination with plasmid DNA expression ...