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Modeling of phototransduction in vision systems
(University of Missouri--Columbia, 2007)
To improve the usefulness of the electroretinogram (ERG) in identifying the sites and mechanisms of adaptation, development and disease processes, a quantitative model was developed based on the biochemical reaction kinetics ...
Development of a biosensor for the detection of Helicobacter hepaticus utilizing multi-functioning immobilization platforms
(University of Missouri--Columbia, 2010)
Optical biosensor development is a process involving the careful selection of the material for the immobilization platform, design of the detection mechanism and integration with optical and electronic equipment. The ability ...
A simplified holistic model of pulmonary oxygen transfer and its application in assessing exercise ability of pulmonary patients
(University of Missouri--Columbia, 2023)
[EMBARGOED UNTIL 5/1/2024] Cardio-respiratory fitness is important in predicting health outcomes as it reflects one's capability to deliver and utilize oxygen. In this research, we first developed a simplified holistic ...
Design and characterization of a hand-held, waveguide-mediated, optoacoustic imaging probe for analyzing burn wounds
(University of Missouri--Columbia, 2018)
Clinicians correctly diagnose only [about]66% of burn wounds, which may be in part due to the qualitative methods commonly employed for burn assessment. This often results in over diagnoses, which may lead to unnecessary ...
Synthesis and application of semiconductor quantum dots in novel sensing applications
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] This thesis details the synthesis of CdSe/ZnS semiconductor nanocrystals (quantum dots). These quantum dots (QDs) show very interesting optical properties ...
Regulation of calcium signaling by p130PH in astrocytes
(University of Missouri--Columbia, 2009)
Ca2+ signaling is a characteristic form of astrocyte excitability, but its role in ischemia is not clearly understood. Our previous study (Ding et al., 2009) demonstrated that astrocytes exhibit enhanced Ca2+ signaling ...
Engineering nanomaterials for cancer theranostics
(University of Missouri--Columbia, 2021)
This thesis aims to engineer novel nanomaterial to target receptors on the surface of cancer to diagnose and deliver cytotoxic drugs or siRNA selectively. Receptor-targeting peptides have been relatively unexplored to ...
Development of a fluorescence resonance energy transfer optical nanoscale biosensor based on a liquid-core waveguide platform
(University of Missouri--Columbia, 2007)
In order to produce a more versatile, adaptable, and effective method for detection of biological analytes, a self-contained and robust fluorescent optical biosensor architecture utilizing fluorescence resonance energy ...
Modeling the impact of polystyrene microparticles on toxicity of phenol to Artemia
(University of Missouri--Columbia, 2011)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The increasing use and availability of micro and nanoparticles for use in science, technology and daily consumer products has led to unique challenges ...
Degradation of the veterinary antibiotics in swine manure via anaerobic digestion
(University of Missouri--Columbia, 2021)
Antimicrobial resistance is becoming an imminent danger for human health, in part because of excessive consumption of antibiotics in the animal industry. Laboratory-scale anaerobic digesters (ADs) were utilized to investigate ...
Modeling of delayed fluorescence from photosystem II and applications in assessment of drought and chemical stresses
(University of Missouri--Columbia, 2009)
Photosynthesis is not only vital for plant growth and survival but also indicative of plant-environment interactions. This research was designed to analyze photoelectron kinetics and its dependence on environmental factors. ...
Green solvent-enabled biomass conversion for renewable chemicals and lignin upgrading
(University of Missouri--Columbia, 2018)
Lignocellulosic biomass, which is mainly composed of cellulose, hemicellulose, and lignin, is a promising feedstock for producing renewable chemicals and fuels. To make lignocellulosic biomass-based refinery (biorefinery) ...
Novel methods for quantifying lung and cardiac diseases with magnetic resonance imaging
(University of Missouri--Columbia, 2023)
[EMBARGOED UNTIL 5/1/2024] Magnetic Resonance Imaging (MRI) is an advanced imaging technique that has transformed the field of medical diagnosis and treatment. In the field of lung and cardiac imaging, MRI boasts the ...
Nanofibrillation of lignocellulosic biomass into lignin-containing nanocellulose for 3D printing and antimicrobial applications
(University of Missouri--Columbia, 2022)
Lignin-containing nanocellulose (LNC) has become an emerging subcategory of nanocellulose. Compared toedtraditional pure nanocellulose, LNC contains lignin and hemicellulose that are not fully removed from original ...
Targeted therapeutics for non small cell lung carcinoma
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] "Lung carcinoma, also known as lung cancer, is a malignant tumor of lungs characterized by uncontrolled call growth in lung tissue. Tobacco smoking ...
I. Infection control: exploration of siliceous zeolite MFI films as coatings for implantable devices II. Alternative approaches for post-operative infection control using pre-and pro-biotics: a meta-analysis
(University of Missouri--Columbia, 2022)
The prevention and control of infections associated with indwelling medical implants has remained a top goal for biomedical researchers and clinicians in associated fields. Multiple routes have been explored for this ...
Porous silicates for applications in smart water treatment systems and antimicrobial biomedical coatings
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Porous silicates, particularly ordered ones, may find novel and wide-ranging applications in the bioengineering arena in the near future. For instance, ...
Enhanced tissue engineering properties of osteoinductive chitosan hydrogel
(University of Missouri--Columbia, 2022)
Lower back pain is a considerable medical problem that will impact 80 percent of the U.S. population at some point in their life. With the most severe cases, surgical repair is necessary and is associated with costs upwards ...
A novel PCR based DNA microanalyzer system for detection of viral genome
(University of Missouri--Columbia, 2006)
A micro-fluidic assay to quickly analyze microscopic samples of DNA is being developed for field applications. It consists of a micro-PCR chamber, micropumps, and micro-heaters. Additional components of the device include ...
Climate change impacts on hydrologic components and occurrence of drought in an agricultural watershed
(University of Missouri--Columbia, 2018)
The study on potential acceleration of future hydrologic cycle due to change in precipitation and increase in temperature are essential for managing natural resources and setting policy. The impact of future climate change ...