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Phenotypically different cells in the nucleus of the solitary tract : expression of group I metabotropic glutamate receptors and activation by baroreflexes
(University of Missouri--Columbia, 2008)
Modulation and integration of visceral and central afferent information occurs in the nucleus of the solitary tract (NTS). The NTS is a heterogeneous nuclear region that contains afferent terminals, interneurons, and ...
The contribution of titin to striated muscle shortening
(University of Missouri--Columbia, 2008)
Striated muscle shortens under various loads (i.e., performs work), which allows movement of the skeleton and pumping of blood throughout the circulatory system. The amount of work that a muscle can do is determined by the ...
Molecular control of endothelial lumen formation by Rho GTPases in three dimensional collagen matrices
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Rho GTPases regulate a diverse spectrum of cellular functions involved in vascular morphogenesis. Here, we show that Cdc42 and Rac1 play a key role ...
Hypochlorous acid stimulates heme oxygenase-1 gene expression in human endothelial cells
(University of Missouri--Columbia, 2008)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] In the present study, we tested the hypothesis that Hypochlorous acid (HOCl) regulates the expression of the cytoprotective protein heme oxygenase-1 ...
Peroxynitrite, pumps and perivascular adipose tissue : studies across the physiological spectrum
(University of Missouri--Columbia, 2008)
Peroxynitrite (ONOO-) is a reactive nitrogen species produced when nitric oxide (NO) and superoxide (O2-) react. In vivo studies suggest that reactive oxygen species and perhaps peroxynitrite can influence Na,K-ATPase (Na ...
Alcohol induced histone acetylation mediated by histone acetyl transferase GCN5 in liver
(University of Missouri--Columbia, 2008)
Although several mechanisms have identified for alcoholic liver disease, at present there are no precise mechanisms for liver injury. We have observed that surrogate alcohols increases histone H3 acetylation selectively ...