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Use of antisense oligonucleotides to enhance exon 7 incorporation in the pre-mRNA splicing of SMN2
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Spinal muscular atrophy (SMA) is a neurodegenerative disorder that is relatively common in humans and is caused by loss of the survival motor neuron 1 (SMN1) gene. SMA is the leading cause of hereditary infant mortality ...
A kinetic study of active site mutations in GDP-mannose dehydrogenase
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
In the human pathogenic bacterium Pseudomonas aeruginosa, GDP-mannose dehydrogenase (GMD) serves as a critical enzyme in the biosynthesis of alginate, a polysaccharide that functions as a protective coating against antibiotics ...
Target test tube assembly process and design for the development of molybdenum-99 [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Molybdenum-99 (Mo-99) is used to create Tc-99m, a widely used nuclear medicine diagnostic imaging radioisotope. In an attempt to decrease the need for imported Mo-99, development of mechanical systems to efficiently prepare ...
Natural variation in Arabidopsis thaliana: Molecular genetic architecture of stress tolerance under water deficit
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
The functional genomics tools available for studying Arabidopsis thaliana are a great resource for researchers trying to characterize and understand the genetic basis of natural variation. Genome wide transcript profiling ...
The effects of an 8-week low-intensity exercise program on people with arthritis
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
This study analyzes the effects of 8 weeks in the PACE program, a low-intensity exercise program for people with arthritis in the areas of pain, stiffness, function, and physical performance. PACE, which stands for People ...
Do type I collagen defects that cause Osteogenesis Imperfecta result in an inherent muscle pathology? [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Osteogenesis imperfecta (OI) is a congenital connective tissue disorder characterized by decreased bone mineral density and increased bone fragility and susceptibility to fracture. In addition to skeletal fragility, patients ...
Effect of experimental forest treatments on gray treefrog (Hyla versicolor) habitat use [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Amphibian use of modified habitats has recently received more attention due to anthropogenic land-use patterns and the continued decline of species. We examined habitat use and abundance of gray treefrogs (Hyla versicolor) ...
The manifestation of death in Nathaniel Hawthorne's gothic fiction [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Nathaniel Hawthorne is one of the most popular authors of American literature during the 19th century. My research then investigates how Nathaniel Hawthorne's “Alice Doane's Appeal” as well as “The House of Seven Gables” ...
Exploring the obstacles hindering the academic attainment of Latino/a students [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
There are many obstacles that work to hinder the academic attainment of Latino/a students; not only are these students a minority population on most university campuses, but the ratio of Latino/a students to actual state ...
Race relationships in Aphra Behn's Oroonoko [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
A number of scholars classify Aphra Behn's Oroonoko as one of the first anti-slavery or abolitionist narratives. However, my research discusses the seemingly problematic nature of Behn's text because of her decision to ...
Growth of orthographic representations in children with LLD [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
One aspect of word learning from reading is knowledge of the orthographic representation of a word. Children with language-learning disabilities (LLD) might be expected to have greater difficulties than peers acquiring ...
Effects of maternal diet on offspring in terms of behavior and overall health [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Polyunsaturated fatty acids have been touted to affect mammalian health and fecundity. Since stressed rodents tend to produce a surfeit of female pups, we studied the effects of these diets on female offspring behavior. ...
Prediction of superhelical proteins using machine learning methods [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
The main objective is to use three state of the art machine learning methods to find the most efficient way for predicting and characterizing the superhelical proteins based solely on their sequence information. To achieve ...
Parent-adolescent relationships, sibling ordinal status, and adolescent adjustment [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Investigating the possible moderating affects of sibling ordinal status, researchers tested how differences in parent-child communication and trust between first-born and later-born children influence adolescent depressed ...
Grief: A gendered approach to the elegies of Plath and Lowell [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Landmark studies by psychologists Kalish and Reynolds in the 1970s and de Ridder in 2000 have confirmed distinct differences in grieving strategies between men and women, but the complex problem of grief remains ambiguous. ...
Exposure to explicit sexual media impacts men's perceptions of women's motives for sexual intercourse [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Previous studies have shown that exposure to sexually explicit media can influence males' attitudes toward sex and their sexual partners, their behaviors, and their emotions. Researchers found increased aggression towards ...
Thrust and torque response for drilling titanium and carbon composite sandwich materials [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Experiments were conducted based upon previous research conducted by El-Gizawy and Khasawneh [1] to determine the time response of thrust force and torque correlated to a simple drilling procedure through carbon fiber ...
South Korea protein demands [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Over the last 10 years South Korea has had experienced a steady increase in population averaging an increase of approximately 1% a year. They have also been able to acheive economic growth with a GDP that is almost two and ...
Shipping Box Radiation Level Detector
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Shippers at the University of Missouri Research Reactor (MURR) are currently being exposed to radiation while manually testing the radiation level of outgoing shipping boxes. The boxes contain radioactive isotopes used in ...
Protoemics of integral membrane proteins from developing Brassica napus
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
As plant seeds develop the accumulation of natural products, starch, oil, and protein undergo dramatic changes. At the early stages of seed filling in oilseeds starch is the principal component. Oil (triacylglycerol) and ...