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In Pursuit of Extraordinarily Twisted Acenes
(2015-05-26)
Longitudinally twisted acenes are a topologically interesting class of polycyclic aromatic hydrocarbons (PAHs), and it could be argued that they have quite beautiful chemical structures, too. X-ray crystal analysis of many ...
Positron interactions with oriented polymers and with chiral quartz crystals
(University of Missouri--Kansas City, 2017)
Positron annihilation in various materials has been applied to characterize
microstructure for decades. In this work, PALS was used to study material nanostructure,
with a focus on the size and density of free volume ...
Synthesis, Characterization and Device Studies of Conjugated Foldamers
(University of Missouri--Kansas City, 2017)
Conjugated polymers have found a wide range of electronic applications in last few
decades due to their superior combination of optoelectronic, mechanical properties, and
solution processability. In the past few years, ...
Synthesis, self-assembly and applications of tribenzopenta-phene derivatives and triphenylene-based conjugated foldamers
(2013)
Polycyclic aromatic hydrocarbons (PAHs) are interesting discotic liquid crystalline materials. Their often planar or near-planar geometry and extended π-delocalization render them appealing π-π stacking building blocks ...
Pressure-induced phase transitions in select molybdates and tungstates
(2013)
Mao-Bell and symmetric diamond anvil cells were used to study the effect of
high-pressure on a series of tungstate and molybdate compounds. The experimental
techniques of powder x-ray diffraction and Raman spectroscopy ...
Polycyclic Aromatic Hydrocarbon (PAH)-Based Conjugated Macrocycles and Polymers For Electronic Applications
(2014)
Due to the high tendency to form π-stacked ordered phases, polycyclic aromatic hydrocarbons (PAHs) are attractive building blocks for the assembly of conjugated systems for electronic applications. The body of this ...
Long Term Ocular Drug Delivery with Novel Pentablock Copolymers; Part I: Composite Nanoformulation of Macromolecules For Back of the Eye Diseases, Part II: Dexamethasone Nanoparticle to Develop an In Vitro Model for Glaucoma
(University of Missouri -- Kansas City, 2017)
Pentablock (PB) copolymers have been successfully synthesized for long term delivery in
the treatment of posterior segment ocular diseases. PB copolymers are comprised of FDA
approved biodegradable polymer such as ...
Raman, Infrared and Microwave Spectra, Conformational Stability, R₀ Structural Parameters and Vibrational Assignments of Some Organoamines, Organophosphines, Alcohols And Substituted Four And Five Membered Rings
(2014)
The infrared and Raman spectra of compounds with amino, phosphours, silane and hydroxyl functional groups, as well as some with cyclic skeletal structures have been recorded of the gas and in condensed phases. Temperature ...
Development of polymeric nanoparticulate formulation encapsulating protein molecules following hydrophobic ion pairing complexation
(2014)
Several formulation strategies have been employed to enable sustained delivery of antibody therapeutics by nanoparticulate based dosage forms. However, development of sustained release nanoparticulate based dosage form for ...
Photoemission Spectroscopy Studies of New Topological Insulator Materials
(2015-08-04)
As the size of a solid shrinks, the ratio of surface area to bulk volume grows and
surface effects become more important. In a world where technologies advance with the
shrinking size of electronic devices, one phase of ...
Protein production and applications of NMR in pharmaceutical sciences
(2014-08-28)
The objective of Part I (Protein production for structural elucidation using NMR) is to design and develop strategies of producing amyloid beta protein for structural analysis using NMR. Amyloid beta oligomers are considered ...
Uranium Oxides for Solid-State Direct-Conversion Neutron Detection
(2020)
to achieve absorption probabilities of a few percentages: 1.5–4% for 10 MeV neutrons for natural uranium oxides, ∼2% for 1 MeV neutrons for ²³⁵U-based uranium oxides, and 7–9% for thermal neutrons for natural uranium oxides, assuming each detector is 1 cm...
Novel nanocarriers to improve drug delivery for age-related macular degeneration
(2021)
Visual impairment affecting the posterior segment of the eye is a significant health problem causing a deterioration of the quality of life of millions worldwide. Age-related macular degeneration (AMD) is ranked third on ...
Novel targeted lipid prodrugs to improve cellular absorption of acyclovir and topical delivery to the eye via nanomicellar approach
(2013)
Biotinylated lipid prodrugs of acyclovir (ACV) were designed to target the
sodium dependent multivitamin transporter (SMVT) on the intestine and cornea to
facilitate ACV cellular transport. All the prodrugs were screened ...
Development of Pentablock Copolymer Based Formulations for the Sustained Delivery of Protein Therapeutics in the Treatment of Posterior Segment Ocular Diseases
(2013)
We have successfully synthesized pentablock (PB) copolymers comprised of various FDA approved polymer blocks such as polyethylene glycol (PEG), polycaprolactone (PCL), polylactic acid (PLA) and polyglycolic acid (PGA). PB ...
On the advancement of core/shell titanium dioxide nanomaterials for microwave absorption
(2020)
Controlling the interactions between incident electromagnetic energy and matter is of critical importance for many civil and military applications, such as photocatalysis, solar cells, optics, radar detection, communications, ...
Library Screening and Focused Multiomics of Antibacterial Action on Vancomycin-Resistant Enterococci faecium
(2023)
in VRE faecium. Therefore, gene induction was observed using both low (1/4th x MIC) and high (4x MIC) of an antibiotic. Furthermore, mutagenesis study was also done using MRSA. In this study, mutants of MRSA were generated on resistant antibiotic plates...
Pentablock copolymers based controlled release formulations of small and macromolecules for ophthalmic applications
(University of Missouri--Kansas City, 2012)
Pentablock copolymers comprised of multi-polymer blocks such as polyethylene
glycol (PEG), polycaprolactone (PCL) and poly-lactide (PLA) were developed for
fabrication of nanoparticles and thermosensitive hydrogel ...
Mathematical Analysis of Compressive/Tensile Molecular and Nuclear Structures
(2015-06-19)
Mathematical analysis in chemistry is a fascinating and critical tool to explain
experimental observations. In this dissertation, mathematical methods to present
chemical bonding and other structures for many-particle ...
Development of Advanced Delivery Systems for Microbicides
(2016)
HIV/AIDS still continues to be a pandemic and global emergency and is a leading cause of
death among the women of reproductive age (15-49 yr). Women are more vulnerable for HIV infection
due to anatomical and physiological ...