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Viroids : minimal genetic systems : (RNA, plant pathogens, replication, pathogenesis)
(University of Missouri, Agricultural Experiment Station, 1980)
are not encapsidated. Despite their small size, viroids replicate autonomously in cells of susceptible plant species. Known viroids are single stranded, covalently closed circular, as well as linear, RNA molecules with extensive regions of intramolecular...
DNA packaging in isolated bacterial nucleoids : (chromosomes, DNA tertiary structure, nucleoids, DNA folding, DNA supercoiling, nascent RNA, membrane-DNA)
(University of Missouri, Agricultural Experiment Station, 1976)
Properties of nucleoids isolated from Escherichia coli are described. Experiments which investigate the organization of DNA folding and supercoiling in the isolated chromosome are reviewed, and evidence is discussed suggesting a role for certain...
Divergent and concerted evolution of the two regions encompassing the iso-1- cytochrome c and iso-2-cytochrome c genes of yeast : (saccharomyces cerevisiae, cytochrome c of yeast, evolution of yeast, cloning yeast genes, recombinant DNA, transpositions, composite genes)
(University of Missouri, Agricultural Experiment Station, 1982)
transposition in which a circular intermediate containing the three genes integrated at a new chromosomal position. The order of the genes could have been altered if the circle closed and opened at different sites during the excision and integration...
Ti plasmids of agrobacterium : potentials for genetic engineering : plasmids, genetic engineering, crown gall, tumors
(University of Missouri, Agricultural Experiment Station, 1979)
Crown gall disease of dicotylendenous plants, induced by Agrobacterium tumefaciens, provides a unique system for the study of pathogen-host interplay at the molecular level. By means of large Ti plasmids borne by virulent ...
Genetic approaches to the study of ribosomes
(University of Missouri, Agricultural Experiment Station, 1976)
Specific mutants of Escherichia coli have been used in order to investigate certain aspects of ribosome function, bio synthesis and decay. These studies show that in the function of the ribosome its various components are ...
Genetic Regulation of fermentation organisms : fermentation, regulation, antibiotics
(University of Missouri, Agricultural Experiment Station, 1976)
An effective fermentation organism is a wasteful creature that overproduces and excretes its metabolic intermediates and end products. Cultures obtained from screening programs usually possess subnormal regulatory controls. ...
The integration of human DNA and expression tumor virus genes : (cell transformation, transcription, integration, human cancer)
(University of Missouri, Agricultural Experiment Station, 1980)
DNA tumor viruses offer excellent model systems to study the molecular biology of eucaryotic cells and to establish the molecular basis for cell transformation. Our laboratory has focused on the human adenovirus type 2 ...
Evolution of DNA sequence : mechanisms and models as seen in small phages : (small isometric phages, evolution of their nucleotide sequence, duplication, deletion, overlapping genes, secondary structure)
(University of Missouri, Agricultural Experiment Station, 1980)
Extensive nucleotide sequence data is new known for six small isometric phages, ([o with diagonal slash]Xl 74, G4, St-1, Sl3, [lowercase alpha]3 and [phi]K).Comparison of these sequences allows us to observe the role of ...