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What is the best treatment for plant-induced contact dermatitis?
(Family Physicians Inquiries Network, 2013)
It's unclear which treatment is best, because there have been no head-to-head comparisons of treatments for Rhus (plant-induced) contact dermatitis. That said, topical high-potency steroids slightly improve pruritus and ...
Pharmacologic therapy for eustachian tube dysfunction
(Family Physicians Inquiries Network, 2013)
There are no medications that improve patient-oriented outcomes in children or adults with eustachian tube dysfunction. (Strength of Recommendation [SOR]: A, based on a systematic review of randomized controlled trials [RCTs].) Oral corticosteroids...
Management of ADHD in preschool-aged children
(Family Physicians Inquiries Network, 2013)
RCTs.) Alternative therapies, such as elimination diets, have limited evidence of success and should generally be avoided or used in conjunction with standard therapies. (SOR: B, based on a systematic review of a small number of heterogeneous RCTs.)...
Is this pregnancy viable?
(Family Physicians Inquiries Network, 2013)
of recommendation: A: Based on a systematic review and meta-analysis of 26 diagnostic accuracy studies....
How do antidepressants affect sexual function?
(Family Physicians Inquiries Network, 2013)
Evidence-based answer: patients treated with elective serotonin reuptake inhibitors (SSRIs) and the serotonin/norepinephrine reuptake inhibitor (SNRI) venlafaxine have significantly higher rates of overall sexual dysfunction--including desire...
Ramipril for claudication?
(Family Physicians Inquiries Network, 2013)
This ACE inhibitor can help patients with peripheral artery disease walk longer while remaining pain free.
How can pregnant women safely relieve low-back pain?
(Family Physicians Inquiries Network, 2013)
Acetaminophen is safe for use in pregnancy but lacks evidence of efficacy (strength of recommendation [SOR]: C, usual practice). Both physical therapy and water aerobics reduce sick days caused by low-back pain (strength of recommendation [SOR]: B...
Do patients with type 2 diabetes who aren't taking insulin benefit from self-monitoring blood glucose?
(Family Physicians Inquiries Network, 2013)
reviews and meta-analyses of disease-oriented evidence). Patients with a baseline HbA1c <8% who self-monitor don't reduce their HbA1c levels, but patients with a baseline HbA1c >8% do (SOR: B, systematic reviews and meta-analyses of disease...
Elevated troponin but no CVD: what's the prognosis?
(Family Physicians Inquiries Network, 2013)
of known cardiovascular disease (TABLE)1-6 (strength of recommendation: B, meta-analysis, multiple prospective and retrospective observational studies.)...
Dipstick urinalysis for the diagnosis of acute UTI
(Family Physicians Inquiries Network, 2013)
. (Strength of Recommendation [SOR]: A, based on systematic reviews of cross-sectional studies and a validated clinical decision rule.) A positive nitrite test is more useful than a positive leukocyte esterase (LE) test, although both increase the odds of a...
Does metformin prevent diabetes in at-risk adults?
(Family Physicians Inquiries Network, 2013)
Metformin therapy reduces the risk of developing diabetes for adults with one or more risk factors for at least 5 years (strength of recommendation [SOR]: A, consistent meta-analyses) and perhaps as long as 10 years (SOR: ...
Missouri hospitalist, issue 48 (2013 July-September)
(University of Missouri. Department of Medicine. Division of Hospital Medicine, 2013-07)
Does caffeine intake during pregnancy affect birth weight?
(Family Physicians Inquiries Network, 2016)
Q: Does caffeine intake during pregnancy affect birth weight? Evidence-based answer: No. Reducing caffeinated coffee consumption by 180 mg of caffeine (the equivalent of 2 cups) per day after 16 weeks-gestation doesn't affect birth weight. Consuming...
What's the best secondary treatment for patients who fail initial triple therapy for H pylori?
(Family Physicians Inquiries Network, 2018)
Q: What's the best secondary treatment for patients who fail initial triple therapy for H pylori? Evidence-based answer: treating patients with Helicobacter pylori infection who have failed clarithromycin-based triple therapy with either...
Who will build the better ape?
(Rhetoric and Composition Program, University of Missouri, 2013)
When I examine the driving forces of progress in modern humanity, I cannot help but recall author Leo Frankowski's musings on the subject of genetic manipulation as a way to drive human evolution. He posed a simple question: ...
Can unintended pregnancies be reduced by dispensing a year's worth of hormonal contraception?
(Family Physicians Inquiries Network, 2019)
Q. Can unintended pregnancies be reduced by dispensing a year's worth of hormonal contraception? Evidence-based answer: probably, although studies that looked directly at this outcome are limited. A systematic review showed that women who received a...
A therapist survey of evidence-based practices in publicly funded youth mental health
(University of Missouri--Columbia, 2018)
sizes in controlled clinical trials for evidence-based treatments (EBTs) for youth MH problems (Weisz, Jensen-Doss & Hawley, 2006). One potential reason for this discrepancy may be that therapists within TAU contexts are not implementing EBTs. To date...
Time to stop glucosamine and chondroitin for knee OA?
(Family Physicians Inquiries Network, 2018)
Time to stop glucosamine and chondroitin for knee OA? Prior studies provided conflicting results regarding the efficacy of these medications. This study offers evidence for discontinuing them. Practice changer: Tell patients with moderately severe...
How effective and safe is fecal microbial transplant in preventing C difficile recurrence?
(Family Physicians Inquiries Network, 2018)
Q: How effective and safe is fecal microbial transplant in preventing C difficile recurrence? Evidence-based answer: fecal microbial transplant (fmt) is reasonably safe and effective. In patients who have had multiple Clostridium difficile...
Trauma care : don't delay with TXA
(Family Physicians Inquiries Network, 2009)
Ensure that patients who incur serious trauma receive tranexamic acid (TXA) within 3 hours of the injury. Stength of recommendation: B: An analysis of a large randomized controlled trial (RCT).