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Should we change formula for a formula-fed infant with persistent spitting up, but with adequate weight gain?
(Family Physicians Inquiries Network, 2001)
We found no controlled trials evaluating the efficacy of changing formulas in the management of uncomplicated regurgitation. However, the evidence suggests that no benefit can be expected from changing formulas, including ...
At what age do patients no longer need colorectal cancer screening?
(Family Physicians Inquiries Network, 2001)
Good evidence supports fecal occult blood testing (FOBT) for patients up to age 75 (grade of recommendation: A, based on systematic review of randomized controlled trials). There is insufficient evidence to recommend for ...
What is the best way to screen for breast cancer in women with implants?
(Family Physicians Inquiries Network, 2008)
Mammography is best. It is considered as effective for screening women who have undergone augmentation mammoplasty as those who have not (strength of recommendation [SOR]: B, limited number of retrospective and prospective ...
Consider this option for heavy menstrual bleeding
(Family Physicians Inquiries Network, 2011)
Offer tranexamic acid to patients with heavy menstrual bleeding. The extended-release formulation is effective and well tolerated. Stength of recommendation: A: Based on 1 good-quality randomized controlled trial (RCT).
Skip the compression stockings following DVT
(Family Physicians Inquiries Network, 2014)
Although commonly used, compression stockings do not effectively prevent post-thrombotic syndrome. Practice changer: Do not recommend elastic compression stockings (ECS) to decrease the incidence of post-thrombotic syndrome (PTS) after deep vein...
Patients insist on antibiotics for sinusitis? Here is a good reason to say no
(Family Physicians Inquiries Network, 2008)
and create unnecessary expense. Stength of recommendation: A: Based on a meta-analysis of 9 randomized trials in primary care practice....
Do imaging studies aid diagnosis of acute sinusitis?
(Family Physicians Inquiries Network, 2003)
Accurate diagnosis of acute sinusitis in both children and adults depends on the history and clinical examination of the patient. While the clinical signs and symptoms of acute sinusitis are often difficult to distinguish ...
Does red wine reduce cardiovascular risks?
(Family Physicians Inquiries Network, 2010)
Moderate daily red wine consumption decreases cardiovascular risk compared with either abstinence or heavy and binge drinking (strength of recommendation [SOR]: B, meta-analysis of prospective cohort and case-control ...
What is the best way to distinguish type 1 and 2 diabetes?
(Family Physicians Inquiries Network, 2005)
No clinical characteristic or diagnostic test is available to readily distinguish type 1 from type 2 diabetes mellitus. Although C-peptide levels, autoantibodies, and adiponectin-to-leptin ratios show some utility, they ...
What is the best treatment for oral thrush in healthy infants?
(Family Physicians Inquiries Network, 2008)
Nystatin oral suspension is a safe first-line therapy; fluconazole is more effective (strength of recommendation [SOR ]: B, 1 small randomized controlled trial [RCT]) but has not been approved by the Food and Drug ...
What is the best way to evaluate secondary infertility?
(Family Physicians Inquiries Network, 2007)
The work-up for secondary infertility--the inability to conceive after 1 year of regular unprotected intercourse for a couple who have previously had a child--should include a history and physical exam for both patients, ...
What are the best treatments for herpes labialis?
(Family Physicians Inquiries Network, 2007)
There are 3: valacyclovir, acyclovir, and topical penciclovir. Valacyclovir, 2g twice in 1 day taken during the prodromal stage of herpes labialis, reduces the episode duration and time to healing. Acyclovir, 400 mg, taken ...
What is the best way to diagnose a suspected rotator cuff tear?
(Family Physicians Inquiries Network, 2006)
The evaluation of a suspected rotator cuff tear should start with a history and a clinical exam of the shoulder (strength of recommendation [SOR]: B, based on a systematic review of cohort studies). Three clinical test ...
What are the indications for bariatric surgery?
(Family Physicians Inquiries Network, 2005)
No studies evaluate the commonly used indications for bariatric surgery. Consensus guidelines suggest that the surgical treatment of obesity should be reserved for patients with a body-mass index (BMI) >40 kg/m2 or with ...
What is appropriate management of iron deficiency for young children?
(Family Physicians Inquiries Network, 2006)
Infants and toddlers with suspected irondeficiency anemia (IDA) should begin treatment with oral ferrous sulfate (3 mg/kg/d of elemental iron). A rise in hemoglobin >1 g/dL after 4 weeks supports the diagnosis of iron ...
Does regular exercise reduce the pain and stiffness of osteoarthritis?
(Family Physicians Inquiries Network, 2008)
Exercise helps reduce the pain, but it's unclear whether it helps with stiffness. Exercise moderately reduces pain in elderly patients with osteoarthritis (strength of recommendation [SOR]: A, 3 systematic reviews, including ...
Do preparticipation clinical exams reduce morbidity and mortality for athletes?
(Family Physicians Inquiries Network, 2005)
Though clinical preparticipation exams (PPE) are recommended by experts and required in most states, we found no medium- or better-quality evidence that demonstrates they reduce mortality or morbidity. PPEs detect only a ...
What findings distinguish acute bacterial sinusitis?
(Family Physicians Inquiries Network, 2003)
No combination of clinical findings can reliably distinguish acute viral rhinosinusitis from acute bacterial rhinosinusitis in primary care. Although unreliable, the best clinical predictor of acute bacterial sinusitis is ...
What is the best therapy for superficial thrombophlebitis?
(Family Physicians Inquiries Network, 2004)
For proximal saphenous vein thrombosis, anticoagulation is more effective than venous ligation (with or without stripping) in preventing deep venous thrombosis (DVT) and pulmonary embolus (PE) (strength of recommendation ...
Is therapy based on endoscopy results better than empiric therapy for dyspepsia?
(Family Physicians Inquiries Network, 2005)
In the initial management of dyspepsia for patients without "alarm" symptoms (weight loss, recurrent vomiting, dysphagia, anemia, evidence of bleeding, onset of dyspepsia after age 45 years), therapy based on the results ...