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What role does phosphorylation of cardiac troponin I play in elevating cardiac contractility following adrenergic stimulation?
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Myocardial performance is enhanced when adrenergic receptors are stimulated by catecholamines. The enhanced performance is mediated by cAMP dependent protein kinase A (PKA), which phosphorylates several proteins within the ...
What's in a worm; Uncovering polymophisms in soybean cyst nematode parasitism genes that correlate with virulence
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Soybean cyst nematode (SCN) is a parasitic worm that penetrates and infects soybean roots resulting in billions of dollars in crop loss annually. The most cost effective and environmentally friendly SCN management strategy ...
Offspring sex ratio varies with maternal condition in mice
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Field and laboratory animal studies have demonstrated that maternal body condition can directly cause adjustments in offspring sex ratio. A mother's condition is affected by a variety of environmental and endogenous factors, ...
Bovine oocyte permeability in 1, 2-propanediol
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Cryopreservation of oocytes is of great importance both in medical research and in the agricultural industry. Cryopreservation of oocytes allows for future breeding of selected genetic lines of animals. Effective ...
Therapy of experimental allergic encephalomyelitis under circumstances relevant to human multiple sclerosis
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Experimental allergic encephalomyelitis (EAE) is an inflammatory disease of the central nervous system (CNS) that resembles human multiple sclerosis (MS). EAE and MS develop when proteins of the myelin sheath that covers ...
Effect of baicalein on regulation of a phase II enzyme in human prostate cancer cell line (PC-3)
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Prostate cancer is an excellent candidate disease for chemo prevention because it is typically diagnosed in elderly males, therefore even a modest delay in the neoplastic development achieved through pharmacological or ...
Going for a triple play: Making a GLH-1; GLH -4; KGB-1 triple mutant
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Essential to the germline determination of the nematode Caenorhabditis elegans are RNA-protein complexes found in germ cell cytoplasms known as P granules. Germline RNA helicase (GLH) proteins are components of P granules ...
Development of chick embryo explant cultures as an assay system to test mammalian stem cell migration and differentiation after transplantation
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Stem cells are undifferentiated cells capable of achieving multiple developmental fates. The embryonic stem (ES) cell can differentiate into all cells of the body. Our stem cell research focuses on the repair and/or renewal ...
Selective precipation of seed storage proteins in soybeans: Reducing the dynamic range of protein expression for in-depth proteome studies
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Seed storage proteins (SSPs) are a class of proteins which accumulate at high levels (up to 60% total protein) during plant seed development as a nitrogen reserve for germination. Due to the preponderance of SSPs, the ...
A computational model for genetically inherited depression
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Depression, or major depressive disorder (MDD) is one of the most disabling and prevalent disorders. It is seen in all age groups, both genders, and all races. One of the biggest problems of depression is the frequency of ...
The key to unlock the Navier-Stokes Equation
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
The key to unlock the Navier-Stokes Equation What causes the waves to break, as they get closer to the shore? Can the strain on the heart to pump blood throughout our bodies be decreased if vortices were eliminated? When ...
Hydrogen storage in diamond powder utilizing naf for fuel cell applications
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Hydrogen Fuel Cells offer the vital solution to the world's socio-political dependence on oil. Due to existing difficulty in safe and efficient hydrogen storage for fuel cells, storing the hydrogen in hydrocarbon compounds ...
Dietary genistein influences function of mouse aorta
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Cardiovascular disease is the leading cause of death for men and postmenopausal women in the United States. Estrogen is thought to be cardioprotective. An important action of estrogen is increasing endothelial-dependent ...
Okara as a novel prebiotic ingredient in the manufacture of a probiotic yogurt
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Okara is a by-product of tofu and soymilk manufactures. High in protein, vitamin B group and antioxidants, okara is very nutritious. Preliminary studies demonstrated okara to be a promising prebiotic, compounds that can ...
The IUBMB enzyme nomenclature decision tree
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
This project attempts to map the decisions involved in categorizing an enzyme using the International Union of Biochemistry and Molecular Biology (IUBMB) enzyme nomenclature. The recommendations of the Nomenclature Committee ...
The use of primary dermal fibroblast cultures to evaluate type I collagen expression in the oim model mouse
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Osteogenesis imperfecta type III is a heritable disorder leading to impaired connective tissue function in type I collagen containing tissues including bone fragility, blue-grey sclera, short stature, and hearing loss. ...
What do pink pigs and soybeans have in common? Selecting for mutants in the ureide pathway
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Pink Pigmented Facultative Methylotrophic bacteria (PPFMs) have been found to be the most abundant microorganisms among phylloplane microflora, and have been recovered from all plants examined. PPFMs are seed-transmitted ...
The effects of oncogenic Ras on the ocular lens
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Ras is a small GTP-binding protein in the signal transduction machinery. In most cell types, activation of Ras by growth factors is essential for normal cell proliferation. A mutation in the Ras gene can lead to a constitutive ...
Impact of creep feeding on subsequent performance and plasma parameters of feedlot steers
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
A study was conducted to evaluate the impact of creep feeding and protein sources, notably DDGS, on blood plasma variables and growth in crossbred steer calves. Thirty-six crossbred steer calves were used in a randomized ...
From pyruvate to PEP...the unknown pathway
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Soybean is a major crop in the United States. Its survival and relationship with its environment are closely monitored. For example, we are looking at the symbiotic relationship between soybean and the soil bacteria. These ...