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Functional study of Kcv potassium channel through manipultion [sic] of individual subunits
(University of Missouri--Columbia, 2010)
Potassium channels make up a ubiquitous, physiologically essential class of integral membrane proteins. Many K+ channels contain four identical symmetrically associated subunits. To explore the role of an individual subunit ...
Manure management using precision agriculture
(University of Missouri--Columbia, 2010)
The overall purpose of this project was to develop and implement a manure application record system that was solely based on Global Positioning Systems (GPS). This system will have the ability to provide steering and ...
Amyloid- [beta] peptide induces temporal membrane biphasic changes in astrocytes through cytosolic phospholipase A₂
(University of Missouri--Columbia, 2010)
Oligomeric amyloid-[beta] peptide (A[beta]) is known to induce cytotoxic effects and damage cell functions in Alzheimer's disease. However, mechanisms underlying the effects of A[beta] on cell membranes have yet to be fully ...
Molecularly imprinted polymer labeled with quantum dots for detection of nitroaromatic explosives
(University of Missouri--Columbia, 2010)
A sensing device for explosive compounds is a fundamental step towards the capability to detect the presence of landmines, improvised explosive devices (IEDs), and other unexploded ordinance. To detect high explosive ...
Applications of the opto-fluidic ring resonator for DNA methylation analysis and microfluidic laser development
(University of Missouri--Columbia, 2010)
For several decades, optical ring resonators have played an important role in the field of telecommunications. Within only the past decade however, ring resonators have been applied for the purposes of biological and ...
Geographic information systems used for precision agriculture : knowledge and use by agriculture students at the University of Missouri (MU)
(University of Missouri--Columbia, 2010)
The use of GIS in PA technology helps manage the information intensive environment in production agriculture by intertwining site-specific (within field) management with computer software modeling for analyses and ...
The use of supercritical fluids to process biomass for fuel
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Soybean flakes were extracted using supercritical carbon dioxide at 48.3 MPa and 80 °C, which is a higher temperature than previously reported. Several ...
Study of low noise high throughput microchip device for electrochemical measurement from single cells
(University of Missouri--Columbia, 2012)
We are developing transparent multi- electrochemical electrode arrays on microchips in order to automate measurement of quantal exocytosis of oxidizable transmitter from individual vesicles. In order to achieve low noise ...
Characterization [of] nucleic acids unwinding and exploring its application in miRNA detection in the nanopore
(University of Missouri--Columbia, 2012)
MicroRNAs (miRNAs) are a class of short (~14-27 nucleotides) noncoding RNAs that regulate gene expression at the post-transcriptional level. Aberrant expression of miRNAs has been found in all types of tumors. Reverse ...
Properties of extruded snacks containing tomato and garlic
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Tomato and garlic may provide health benefits due to their bioactive compounds and fibers. The main objective of this study was to investigate the ...
Nanoparticle mediated ablation of breast cancer cells using a nanosecond pulsed electric field
(University of Missouri--Columbia, 2013)
In the past, both nanomaterials and various heating modalities have been researched as means for treating cancers. However, many of the current methodologies have the flaws of inconsistent tumor ablation and significant ...
Regulation of L-type calcium channel sparklet activity by PKC and C-src
(University of Missouri--Columbia, 2010)
Ca2+ sparklets are elementary fluorescence events associated with Ca2+ entry through L-type Ca2+ channels (Cav1.2) channels and are classified as persistent and low activity Ca2+ sparklets. Persistent Ca2+ sparklets are ...
A modeling approach to ultrasound evaluation of material properties
(University of Missouri--Columbia, 2010)
A method for estimating the mechanical properties of a viscoelastic sample from ultrasound measurements was developed. The sample was represented as a mechanical network according to the Kelvin-Voigt model and linear ...
Photoacoustic detection of circulating tumor cells
(University of Missouri--Columbia, 2013)
Photoacoustics is one of the new branches in biomedical diagnostics that holds lot of new promises and advancements. It is a unique field that deals with the conversion of photons into ultrasound waves. It is only in the ...
Pupillary Light Reflex Deficits in a Canine Model of Neuronal Ceroid Lipofuscinosis and the Effects of Enzyme Replacement Therapy
(University of Missouri--Columbia, 2013)
Pupil size is controlled by the autonomic nervous system, and iris behavior reflects a balance of input from both the sympathetic and parasympathetic nervous systems. The pupillary light reflex (PLR) occurs in response to ...
Development of gold nanoparticle conjugated polyethylene terephthalate for improved biocompatibility in hernia repair materials
(University of Missouri--Columbia, 2010)
Synthetic biomaterials are currently a popular choice for use in many surgical soft tissue repair applications. Polyethylene terephthalate (PET) is an example of such material that has been used, more specifically, for ...
Development and characterization of gold nanoparticle-collagen scaffold
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Collagen is considered a versatile biological material for soft tissue application, owing to its excellent biocompatibility. However in its purified ...
Ion transport modeling for retinal rod photoreceptor cells
(University of Missouri--Columbia, 2010)
In this study, a mathematical model is developed to describe the ion transport activities associated with the response of rod photoreceptor to light stimulus. In the model, the cell body is modeled as two capacitors connected ...
Rapid isolation of target bacteria from complex matrices
(University of Missouri--Columbia, 2010)
The long term goal of the research effort in our group was to develop a new rapid diagnostic process for sepsis. The specific project described in this work aims to obtain these "pure" isolates of the infectious bacteria ...
Electromagnetic stimulation of a composite scaffold for wound healing
(University of Missouri--Columbia, 2012)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Decellularized tissues have been investigated as natural sources for tissue scaffolds as synthetic mimicry of the natural extracellular matrix is quite ...