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Unexpected exosites on the surface of matrix metalloproteinase-12 that fine-tune specificity for elastin and collagen V
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
or stroke. Thus, research into the binding site interactions between MMP-12 and macromolecular substrates provides surface characterization of the enzyme and expedites the process of designing artificial inhibitor molecules to selectively inactivate MMP-12...