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Now showing items 281-300 of 322
Development of radiolabeled metal chalcogenide nanoparticles for targeted adiotherapy against an infection
(University of Missouri--Columbia, 2018)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Targeted radiotherapy has been demonstrated to be therapeutic against infections with doses comparable to what a patient would receive for cancer ...
Technetium and rhenium schiff base complexes for nuclear medicine
(University of Missouri--Columbia, 2019)
This dissertation investigates the synthesis of rhenium and technetium Schiff base complexes for potential applications in nuclear medicine. In Chapter 2, a series of mixed ligand Re(III) complexes of the form trans-[Re( ...
Arsenic-72, 77 as a matched pair radiopharmaceutical for imaging and radiotherapy
(University of Missouri--Columbia, 2018)
Radiopharmaceuticals deliver radionuclides to specific target sites via the bifunctional chelate approach, where the radionuclides are chelated with a ligand and linked to a targeting biomolecule. They can be categorized ...
Novel insights into strand cleavage at an abasic site in DNA
(University of Missouri--Columbia, 2022)
Loss of a nucleobases from the deoxyribose backbone of DNA generates Abasic sites in DNA. Abasic sites are the most common unavoidable DNA damage lesion. It is important to understand the properties of Abasic site. The ...
Anisotropic shock response of 1,3,5-triamino-2,4,6-trinitrobenzene (TATB)
(University of Missouri--Columbia, 2020)
The thermo-mechanical response of shock-induced pore collapse has been studied using non-reactive all-atom molecular dynamics (MD) and Eulerian continuum simulations for the molecular crystal 1,3,5-triamino-2,4,6-trinitrobenzene ...
Mixed quantum-classical simulations of intersystem crossing in the exit channel and vibrational adaptive sampling configuration interaction
(University of Missouri--Columbia, 2022)
A computational study using mixed quantum-classical surface hopping simulations was performed for the reaction of O(3P) with dimethylamine and trimethylamine. These reactions produce an OH radical and while the OH radical ...
Design and synthesis of group 8 transition metal complexes for C-C bond forming valorization of carbon dioxide
(University of Missouri--Columbia, 2023)
The abundancy of carbon dioxide (CO2) in Earth's atmosphere combined with its inexpensive cost and low toxicity has made CO2 upconversion to value added products an area of intense interest in catalysis research. While a ...
Spectroscopic studies of transmembrane helical peptides and LC-MS/MS method development and validation for PFAS quantitation
(University of Missouri--Columbia, 2022)
Water hydrogen bonding (H-bonding) to [alpha]-helical transmembrane (TM) peptides is fundamental to understanding the behavior and function of [alpha]-helical peptides, disease pathways, and the development of new drugs. ...
Oxidative molecular layer deposition of redox-active thin-film polymers
(University of Missouri--Columbia, 2022)
Thin film materials research for a more sustainable future is growing rapidly and new techniques for depositing these films are beginning to surface. One such technique is highlight in this body of work using gaseous ...
Acrylate synthesis from carbon dioxide - ethylene coupling catalyzed by first-row transition metal complexes
(University of Missouri--Columbia, 2021)
Carbon dioxide (CO2) is an abundant and renewable carbon source than can be used as feedstock for the synthesis of value-added materials. One such material is acrylic acid, and acrylate derivatives, which can be used in ...
A study of bacterial cellulose confined ionic liquid and deep eutectic solvent gel materials
(University of Missouri--Columbia, 2020)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI--COLUMBIA AT REQUEST OF AUTHOR.] Pollutants have become more prevalent in the air, water, and ground, necessitating the development of technologies that would help, limit, ...
An evaluation of the need for critically refined purification procedures in fluorescent carbon dot syntheses : the ramifications of the ubiquitous presence of reaction by-products on quenchometric and light harvesting applications
(University of Missouri--Columbia, 2021)
Fluorescent carbon dots constitute a novel and intriguing class of nanocarbons that display unique optical properties and can be purportedly generated from virtually any carbon-containing source. For example, the thermal ...
Probing synthesis of L-ascorbic acid in Arabidopsis thaliana genotypes
(University of Missouri--Columbia, 2021)
L-Ascorbic acid (L-AsA), also known as vitamin C, is a crucial vitamin for both plants and animals due to its antioxidant properties and abilities to scavenge harmful reactive oxygen species (ROS). However, some animals ...
Isotope harvesting from the beam dump cooling loop at the facility for rare isotope beams (FRIB)
(University of Missouri--Columbia, 2018)
Isotope harvesting from the beam dump cooling loop of the Facility for Rare Isotope Beams (FRIB) offers usable quantities of many isotopes unavailable anywhere else in the world. Many of these co-produced isotopes are of ...
Deep eutectic solvents : investigation of solvent structure and its applications
(University of Missouri--Columbia, 2017)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Deep eutectic solvents (DESs) represent an alternative class of ionic fluids closely resembling room-temperature ionic liquids (RTILs), they are ...
Intramolecular (4 + 3) cycloadditions of oxidopyridinium ions : towards daphnicyclidin A
(University of Missouri--Columbia, 2023)
[EMBARGOED UNTIL 5/1/2024] N-alkylation of alkyl 5-hydroxynicotinates with electrophiles containing diene functionality produces salts , which can undergo intramolecular (4 + 3) cycloaddition reactions when heated in the ...
Advancing Uranium(III) reductive chemistry through hetroleptic metallocene aryloxide ligand frameworks
(University of Missouri--Columbia, 2023)
This dissertation looks at the reductive chemistry of Uranium (III)bis- pentamethylcyclopentadienyl arylox-ide complexes. For chapter two, the reactivity of two metallocene aryloxide U(III) complexes, [(C5Me5)2U(O-Ar)], R ...
Synthethic pathways to multiple surface functionalization of polyhedral boranes
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] The chemistry of dodecahydro--closo--dodecaborate(2-), closo-[B12H12]2-, and decahydro-closo-decaborate(2-), [B10H10]2-, with different organic ...
UF-CRDS: a pulsed uniform supersonic flow apparatus coupled with continuous-wave cavity ringdown spectroscopy
(University of Missouri--Columbia, 2022)
Investigating low temperature reaction kinetics of elementary reactions is key to understanding many phenomena of astrochemical importance. Since the introduction of CRESU (A French acronym that stands for reactions kinetics ...
Intermolecular (4+3) cycloaddition reaction of oxidopyridinuim ions with silylated dienes, exploring the oxidation chemistry and photochemistry of cycloadducts
(University of Missouri--Columbia, 2022)
The development of endo/exo selectivity of intermolecular (4+3) cycloaddition reactions of an N-methyl oxidopyridinium ion has been studied. Dienes that contain silyl groups, R-groups, and contain both silyl group and ...