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Now showing items 21-40 of 350
Does breastfeeding affect the risk of childhood obesity?
(Family Physicians Inquiries Network, 2016)
breastfeeding rates during the first 3 to 6 months of life don't appear to alter body mass index (BMI) at 11 to 12 years of age (SOR: B, randomized clinical trial [RCT]). Introducing complementary (solid) foods before 3 months is associated with a 30% greater...
Which treatments are safe and effective for chronic sinusitis?
(Family Physicians Inquiries Network, 2016)
Q: Which treatments are safe and effective for chronic sinusitis? Evidence-based answer: for adults with chronic rhinosinusitis (crs), intranasal steroid (ins) therapy is more likely than placebo to improve symptoms (50% ...
Which patients with metabolic syndrome benefit from metformin?
(Family Physicians Inquiries Network, 2016)
Q Which patients with metabolic syndrome benefit from metformin? Evidence-based answer: Patients at highest risk for progression to diabetes benefit from metformin. In patients with metabolic syndrome who are in the ...
Acupuncture for low back pain
(Family Physicians Inquiries Network, 2020)
Clinical Inquiries question: Is acupuncture effective in improving pain relief for low back pain? Evidence-based answer: Acupuncture is an effective treatment for relief from low back pain, even when compared with other interventions (sham...
Does vitamin D without calcium reduce fracture risk?
(Family Physicians Inquiries Network, 2016)
Q: Does vitamin D without calcium reduce fracture risk? Evidence-based answer: No. Supplemental vitamin D without calcium -- in doses averaging as much as 800 IU per day -- doesn't reduce the risk of hip, vertebral, or ...
Ruling out PE in pregnancy
(Family Physicians Inquiries Network, 2020)
Can clinical probability and a high-sensitivity D-dimer test reliably and safely rule out pulmonary embolism during pregnancy? PRACTICE CHANGER: Use a clinical probability score to identify patients at low or intermediate risk for pulmonary embolism...
Hypoglycemia with insulin and sulfonylureas
(Family Physicians Inquiries Network, 2020)
Clinical Inquiries question: In patients with type 2 diabetes mellitus (T2DM), does the combination of insulin and sulfonylurea (SU) increase the risk of hypoglycemia? Evidence-based answer: The incidence of severe hypoglycemia in patients with T2DM...
When to "CAP" off treatment for pneumonia
(Family Physicians Inquiries Network, 2017)
clinical success rates as longer treatment regimens, but is associated with fewer negative patient outcomes....
Need an add-on to metformin? Consider this
(Family Physicians Inquiries Network, 2017)
Need an add-on to metformin? Consider this. Sulfonylureas have been the preferred add-on therapy to metformin for T2DM, but a study finds that DPP-4s have lower risks of death, CV events, and hypoglycemia. Practice changer: ...
Association of first-line antidepressants and incident adverse metabolic effects
(Family Physicians Inquiries Network, 2020)
Clinical Inquiries question: Are first-line antidepressants associated with incident adverse metabolic effects in adults? Evidence-based answer: Selective serotonin reuptake inhibitors (SSRIs) and bupropion statistically significantly increase...
Is it better to take that antihypertensive at night?
(Family Physicians Inquiries Network, 2020)
A large RCT in a primary care setting comparing bedtime to upon-waking administration of antihypertensives answers the question. PRACTICE CHANGER: Advise patients to take blood pressure (BP) medication at bedtime rather ...
What's the best treatment setting for stable PE patients?
(Family Physicians Inquiries Network, 2018)
What's the best treatment setting for stable PE patients? The answer seems to be the outpatient setting. Here's why. PRACTICE CHANGER: Manage patients with acute pulmonary embolism (PE) who are hemodynamically stable in ...
How often does long-term PPI therapy cause clinically significant hypomagnesemia?
(Family Physicians Inquiries Network, 2018)
Q: How often does long-term PPI therapy cause clinically significant hypomagnesemia? EVIDENCE-BASED ANSWER: Rarely. Proton pump inhibitors (PPIs) may be associated with decreases in serum magnesium laboratory values to below 1.6 to 1.8 mg...
Efficacy of a low-carbohydrate or ketogenic diet in preventing patient morbidity and mortality
(Family Physicians Inquiries Network, 2020)
Clinical Inquiries question: What is the efficacy of a low-carbohydrate or ketogenic diet in the prevention of patient morbidity and mortality? Evidence-based answer: Ketogenic diets can reduce seizure incidence in refractory epilepsy (strength...
Steroids during late preterm labor: better later than never
(Family Physicians Inquiries Network, 2017)
Steroids during late preterm labor: Better later than never. Steroids--even when administered in the last leg of the late preterm period--still reduce the likelihood of respiratory complications in newborns. Practice ...
Time to switch to nonsterile gloves for these procedures?
(Family Physicians Inquiries Network, 2018)
Time to switch to nonsterile gloves for these procedures? Are sterile gloves worth the extra cost for common cutaneous surgeries? This systematic review and meta-analysis provides answers. Practice changer: Using nonsterile ...
Can drinking more water prevent urinary tract infections?
(Family Physicians Inquiries Network, 2020)
Can drinking more water prevent urinary tract infections? A high-quality randomized controlled trial says 'Yes'. PRACTICE CHANGER: Advise premenopausal women with recurrent urinary tract infections (UTIs) and low-volume ...
When can exercise supplant surgery for degenerative meniscal tears?
(Family Physicians Inquiries Network, 2017)
When can exercise supplant surgery for degenerative meniscal tears? PRACTICE CHANGER: Recommend supervised exercise therapy to your patients with a medial, degenerative meniscal tear and a minimal history of osteoarthritis ...
A better approach to the diagnosis of PE
(Family Physicians Inquiries Network, 2019)
angiography when evaluating patients for suspected pulmonary embolism unless: (1) the patient has a d-dimer concentration ≥ 1000 ng/mL; or (2) the patient has a d-dimer concentration ≥ 500 ng/mL, PLUS: (A) clinical signs of deep vein thrombosis, (B) hemoptysis...
The benefits--and limits-- of PPIs with warfarin regimens
(Family Physicians Inquiries Network, 2017)
Patients on warfarin + antiplatelet/NSAID regimens are likely to benefit from the gastroprotective effect of PPIs. For patients taking warfarin alone, it's a different story. PRACTICE CHANGER: Prescribe a proton pump ...