Search
Now showing items 41-60 of 250
Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor
(Interdisciplinary Doctoral Student Council at the University of Missouri- Kansas City, 2007)
Polarized epithelial non-human (canine) cell lines stably transfected with human or murine complementary DNA (cDNA) encoding for various efflux transporters (P-gp/MDR1, MRP1, MRP2, and Bcrp1) were used to study transepithelial ...
Net energy content of soybean meal and glycerol for growing and finishing pigs
(University of Missouri--Columbia, 2009)
Net energy systems are widely accepted and utilized throughout Europe. The main net energy systems used are the French INRA, the Dutch CVB and the Danish PPE. These energy systems are not widely accepted in the U.S. due ...
Degradation and transport of veterinary antibiotics and estrogens in a vegetated buffer strip system
(University of Missouri--Columbia, 2022)
Knowledge of veterinary antibiotic (VA) and estrogenic hormone persistence in soil is critical to understanding environmental risks associated with these potential contaminants. Understanding sorption and transport of the ...
Examining dissolution procedure effects on trace and rare earth element concentrations and U/Pb ages in conodonts
(University of Missouri--Columbia, 2022)
The ability to quantitatively date carbonate rocks and shales using geo- and thermochronometry has eluded geologists due to the scarcity of requisite minerals. A small number of investigations have shown that the highly ...
Learning potential in persons with serious mental illness: investigating intra-individual differences in the learning process
(2015-05-19)
Learning potential has been explored as a possible mechanism to predict positive
rehabilitation outcomes in people with SMI (e.g., Green et al. 2000). More recent
research has identified a strong relationship between ...
New equity issues, share repurchases, and the predictability of aggregate stock returns : an international perspective
(University of Missouri--Columbia, 2006)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] This dissertation investigates the predictive effects of the aggregate stock market returns by new equity issues and shares repurchase in a broader ...
The effects of the selective estrogen receptor modulators MPP and raloxifene in normal and cancerous human and murine uterine tissue
(University of Missouri--Columbia, 2007)
The goal of this research was to determine the in vitro and in vivo effects of the Selective Estrogen Receptor Modulators (SERMs), methyl-piperidino-pyrazole (MPP), raloxifene, ICI 182,780 and 17[beta]-estradiol on endometrial ...
Low sensitivity to, and craving for, alcohol in naturalistic and laboratory settings
(University of Missouri--Columbia, 2019)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Low sensitivity to alcohol is a well-established risk factor for the development of an alcohol use disorder. This risk is transmitted along several ...
Disconnecting a Role for DNA Repair in the Pathogenicity of the Human pathogen Cryptococcus neoformans
(2014)
C. neoformans is an opportunistic fungal pathogen causing fatal meningitis and lung infections. Worldwide every year around 625,000 deaths occur due to Cryptococcosis. A basic understanding of Cryptococcus virulence ...
Evaluation of the efficacy of high levels of microbial phytase in broilers
(University of Missouri--Columbia, 2006)
Three experiments were conducted to evaluate the efficacy of high levels of microbial phytase in broiler diets. In experiment one (EXP 1), phytase was included in the diets at 0, 250, 500, 10,000, and 20,000 PU/kg diet. ...
Influence of subclinical hypocalcemia on plasma biochemical parameters, liver histologic changes, and common postpartum diseases in dairy cows
(University of Missouri--Columbia, 2011)
We hypothesized that cows with subclinical hypocalcemia at calving would have greater elevations in liver associated biochemical parameters and non-esterified fatty acid (NEFA) concentrations compared to normocalcemic cows. ...
Strong Consistency of MLE in Nonlinear Mixed-effects Models with Large Cluster Size
(Indian Statistical Institute, 2005)
The search for conditions for the consistency of maximum likelihood estimators in nonlinear
mixed effects models is difficult due to the fact that, in general, the likelihood can
only be expressed as an integral over the ...
Optimal designs for dose-finding in contingent response models
(University of Missouri--Columbia, 2004)
We study D- and c-optimal designs for dose-finding with opposing failure functions. In particular, we study the contingent response models of Li, Durham and Flournoy (1995). In the contingent response model, there are two ...
Mizzou, volume 103, number 1 (2014 Fall)
(MU Alumni Association, University of Missouri, 2014)
Growth and volatility in inter- and intra-national data
(University of Missouri--Columbia, 2008)
Growth and economic fluctuations are negatively correlated at the country level. Least developed countries measures of output volatility are almost double the size of the developed countries counterpart. This paper provides ...
Effects of fescue toxicosis and chronic heat stress on murine hepatic gene expression
(University of Missouri--Columbia, 2006)
Fescue toxicosis affects domestic animals grazing fescue pasture infected with the endophytic fungus, Neotyphodium coenophialum. Signs of fescue toxicosis include increased body temperature and respiration rate and decreased ...
Effects of Selected Contaminants on the Physical, Chemical, and Geotechnical Properties of Aquifer Solid
(2014)
The primary objective of this study was to investigate the potential effects of hydrocarbons on the geotechnical properties of sand. A series of laboratory experiments were carried out to ascertain the influence of some ...
Longitudinal assessment of age-related change in the dental pulp chamber and age estimation using dental radiographs
(University of Missouri--Columbia, 2007)
This dissertation presents a new and practical method of adult age estimation with successful tests of its validity and repeatability. Six qualitative criteria evident in oral radiographs were developed from 37 subjects ...
Effects of heat stress and fescue toxicosis on the immune system and other physiological parameters
(University of Missouri--Columbia, 2010)
Tall fescue is widely used as pasture grass in the United States, and is the most important cool season grass for grazing animals. Certain fungi also grow on these grasses which produce toxins, resulting in reduced feed ...
Uneven-aged management in the Missouri Ozarks: effects of site conditions, stand density, and prior populations on oak regeneration
(University of Missouri--Columbia, 2022)
While studies have shown the importance of site characteristics and overstory density on the success of white oak regeneration under uneven-aged management, few studies have analyzed the effects of these variables over ...