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Effects of culture conditions on cytosine methylation and MeCP2 binding in preimplantation mouse embryos
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Imprinting is an epigenetic modification in which one gene of a pair of alleles is silenced in a parent-specific way. Imprinting is commonly controlled by methylation of the C5 position of cytosines which are located next ...
MCP-1 and its role in lyme arthritis [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Lyme disease is caused by infection with the bacteria Borrelia burgdorferi, causing arthritis and carditis in infected animal models. The presence of spirochetes in the joint and other soft tissues induce recruitment of ...
Host proteins used in HIV assembly and budding
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Human immunodeficiency virus (HIV), the virus responsible for the AIDS pandemic, uses host cell machinery to assist its replication during the viral life cycle. A recent study randomly screened 21,000 host cell genes using ...
Properties of soil samples from below prehistoric Lake Agassiz
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Prehistoric Lake Agassiz, located in present day North Dakota, was a large lake (larger than all of the existing great lakes combined) fed by glacial runoff during the last ice age. The lake created a soft clay soil deposit, ...
How to get through a nanopore and across a bilayer: The difference between linear and folded DNA
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Translocation of DNA through lipid bilayers is essential to cell function for the transcription of RNA and proteins. Alpha hemolysin is the biological nanopore used to translocate DNA across this phospholipid bilayer. There ...
Is it significant: A search for motifs and their possible significance
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Synthetic biology is an emerging field of study based on the chemistry of biological macromolecules. The function of these molecules is determined by their structure and the structures are determined by the sequence. One ...
Wading in the gene pool: Female preference for long mating calls in gray tree frogs (Hyla versicolor)
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Female gray tree frogs (Hyla versicolor) exhibit a clear preference for long mating calls. Moreover, the expression of this preference varies. The "good genes" model of sexual selection suggests that this is because females ...
Microbial fuel cell analysis
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Microbial Fuel Cells (MFC) are under vast considerations of use, by reason of the energy and economic "crisis" that faces many Western world citizens. MFCs have benefits over other renewable energy systems of creating at ...
Characterization of muscle in OI Model mice
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Osteogenesis imperfecta (OI) is a congenital connective tissue disorder characterized by decreased bone mineral density and increased bone fragility and susceptibility to fracture. In addition to skeletal fragility, patients ...
A new approach toward PTP-1B inhibition
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Signaling pathways for cellular metabolism, growth, proliferation, differentiation, immune response, motility, and tissue homeostasis is regulated by the phosphorylation of protein tyrosine residues on target proteins in ...
Effects of polyploidy on female call preference in gray treefrogs, Hyla chrysoscelis
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
The gray treefrog complex consists of two cryptic species; Hyla versicolor is a tetraploid (N=48) species that arose from the polyploidization of its diploid counter-part, H. chrysoscelis (N=24) and two other extinct ...
Significance of hormone replacement therapy in the experience of Lymphedema in breast cancer survivors
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Little is known about the relationship between hormone replacement therapy and Lymphedema (LE), the accumulation of lymph in soft tissue with accompanying swelling that affects 20-40% of breast cancer survivors, mainly in ...
Establishing the status of the American black bear in southern Missouri [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
The current status of the black bear population in Missouri is largely unknown, as we have little to no information concerning its size, reproductive status and origin. However, evidence suggests that the bear population ...
Black Family Life: An African American parenting magazine
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Parenting magazines geared toward strengthening the traditional northern European family have been around for decades. Yet, they have not focused on the different family types or the needs of African American families. ...
Fourier transforms applied to a hydraulic system [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Control valves (i.e. poppet valves) are commonly used in hydraulic systems for accurate control of the system response. These valves can only provide accurate responses for a limited frequency range. The bode plot is a ...
Dengue RdRp characterization [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Dengue virus kills 25,000 people annually in affected tropical regions. Non-structural protein 5 of the virus has RNA-dependent-RNA-polymerase and methyltransferase activity in separate domains. Since genome duplication ...
Identification of H19 polymorphism for an assessment of biallelic expression
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Animals produced from assisted reproductive technologies suffer from developmental abnormalities and early fetal death at a higher frequency than that observed in those produced by natural breeding. These symptoms are ...
A comparative study of the feral horses of Shackleford Banks and Assateague Island [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Feral horses (Equus caballus) can be found today in isolated barrier island populations along the eastern coast of the United States. Assateague Island stretches for 37 miles along the coasts of Maryland and Virginia and ...
Cerebellar white matter abnormalities in phenylketonuria (PKU) [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Phenylketonuria (PKU) is a recessive genetic disorder that is characterized by an individual's body being unable to utilize the amino acid phenylalanine because of a dysfunction with the enzyme phenylalanine hydroxylase. ...
Pathogen susceptibility to Pseudomonas syringae in Arabidopsis thaliana [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Peptides may act as regulatory molecules that coordinate cellular responses needed for growth, differentiation and development. A novel family of small peptides, encoded by the DEVIL (DVL) gene family, was identified in a ...