Search
Now showing items 81-100 of 368
Characterization of muscle in OI Model mice
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Osteogenesis imperfecta (OI) is a congenital connective tissue disorder characterized by decreased bone mineral density and increased bone fragility and susceptibility to fracture. In addition to skeletal fragility, patients ...
99mTc-DPR-SSS-BBN for diagnosis of human cancers [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Receptor-specific, radiolabeled peptides have become increasingly popular as targeting vectors for the development of new diagnostic radiopharmaceuticals. The over-expression of certain receptors such as the gastrin releasing ...
Amyloid Beta peptide's effects on NMDA receptors in PC-12 cells
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Amyloid-Beta peptide (Aß), a causative agent in Alzheimer's disease (AD), is known to deposit on cell membranes, disrupt cell functions, and induce cytotoxic effects including over-production of reactive oxygen species ...
Identification of H19 polymorphism for an assessment of biallelic expression
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Animals produced from assisted reproductive technologies suffer from developmental abnormalities and early fetal death at a higher frequency than that observed in those produced by natural breeding. These symptoms are ...
Dengue RdRp characterization [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Dengue virus kills 25,000 people annually in affected tropical regions. Non-structural protein 5 of the virus has RNA-dependent-RNA-polymerase and methyltransferase activity in separate domains. Since genome duplication ...
A comparative study of the feral horses of Shackleford Banks and Assateague Island [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Feral horses (Equus caballus) can be found today in isolated barrier island populations along the eastern coast of the United States. Assateague Island stretches for 37 miles along the coasts of Maryland and Virginia and ...
Cerebellar white matter abnormalities in phenylketonuria (PKU) [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Phenylketonuria (PKU) is a recessive genetic disorder that is characterized by an individual's body being unable to utilize the amino acid phenylalanine because of a dysfunction with the enzyme phenylalanine hydroxylase. ...
Pathogen susceptibility to Pseudomonas syringae in Arabidopsis thaliana [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Peptides may act as regulatory molecules that coordinate cellular responses needed for growth, differentiation and development. A novel family of small peptides, encoded by the DEVIL (DVL) gene family, was identified in a ...
Significance of hormone replacement therapy in the experience of Lymphedema in breast cancer survivors
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Little is known about the relationship between hormone replacement therapy and Lymphedema (LE), the accumulation of lymph in soft tissue with accompanying swelling that affects 20-40% of breast cancer survivors, mainly in ...
Establishing the status of the American black bear in southern Missouri [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
The current status of the black bear population in Missouri is largely unknown, as we have little to no information concerning its size, reproductive status and origin. However, evidence suggests that the bear population ...
Effects of polyploidy on female call preference in gray treefrogs, Hyla chrysoscelis
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
The gray treefrog complex consists of two cryptic species; Hyla versicolor is a tetraploid (N=48) species that arose from the polyploidization of its diploid counter-part, H. chrysoscelis (N=24) and two other extinct ...
SNP discovery and linkage mapping in Nicotiana
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
We are developing a genetic linkage map in F2 populations descended from a cross between Nicotiana plumbaginafolia and N. longiflora as well as the reciprocal cross. We are using an interspecific cross because is an ...
Efficacy of turmeric (Curcuma longa) to ameliorate the adverse effects of ochratoxin A in broiler chicks
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
A 21-day feeding study was conducted to assess the effectiveness of turmeric (Curcuma longa) powder (TMP), containing a known level of curcumin to offset the adverse effects of ochratoxin A (OA) in broiler chicks. Five pen ...
HIV versus the Terminator: Drug resistance of HIV reverse transcriptase with mutations at the connection subdomain
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Antiretroviral drug therapy can prolong the life of an HIV-infected individual, but this treatment also promotes drug-resistance mutations. The replicative enzyme of HIV, reverse transcriptase (RT), is a primary target for ...
Role of C-reactive protein in a murine model of vein graft disease
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
C-reactive protein (CRP), an acute phase reactant plasma protein, plays a key role in modulating the innate immune system. Elevated plasma levels of CRP are independently associated with increased risk of thrombosis. In ...
Differences in habitat use of gray treefrogs (Hyla versicolor) in experimental forest plots
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
The fragmentation of species' natural habitats has become a topic of particular concern in the past several years. Habitat fragmentation is an especially important consideration for seasonally migrating species such as ...
Black Family Life: An African American parenting magazine
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Parenting magazines geared toward strengthening the traditional northern European family have been around for decades. Yet, they have not focused on the different family types or the needs of African American families. ...
Effects of culture conditions on cytosine methylation and MeCP2 binding in preimplantation mouse embryos
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Imprinting is an epigenetic modification in which one gene of a pair of alleles is silenced in a parent-specific way. Imprinting is commonly controlled by methylation of the C5 position of cytosines which are located next ...
Fragment based screens of the -D-phosphohexomutases as an initial step for inhibitor design
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Enzymes in the -D-phosphohexomutases superfamily frequently play a role in the biosynthesis of carbohydrates and glycolipids, critical for bacterial virulence and growth. -D-phosphohexomutases are being increasingly shown ...
Fourier transforms applied to a hydraulic system [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2008)
Control valves (i.e. poppet valves) are commonly used in hydraulic systems for accurate control of the system response. These valves can only provide accurate responses for a limited frequency range. The bode plot is a ...