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Relative HER2 protein expression in normal canine tissue and canine osteosarcoma
(University of Missouri--Columbia, 2022)
Development of HER2-targeted immunotherapy in canine osteosarcoma (OSA) is underway, yet HER2 expression in normal and neoplastic canine tissue has not yet been defined. This study's objective was to evaluate the relative ...
Topical therapeutic strategies for the treatment of corneal fibrosis in veterinary species
(University of Missouri--Columbia, 2022)
Purpose: To determine the safety and efficacy of a novel combination of TRAM-34 and ascorbic acid applied topically in vivo in native and alkali injured rabbit corneas. Methods: Twelve New Zealand rabbits were randomly ...
Intramammary infections in lactating Jersey cows: prevalence of pathogens and association of pathogen type with milk somatic cell count and persistence of infection
(University of Missouri--Columbia, 2022)
There is limited data available regarding pathogens causing intramammary infections (IMI) in Jersey cows. The objectives of this study were to characterize the prevalence of IMI caused by different microorganisms in lactating ...
The role of Cdc42 Rho GTPase in the cystic fibrosis intestinal epithelial barrier
(University of Missouri--Columbia, 2022)
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. People with CF and CF mouse models experience increased intestinal permeability, but the molecular mechanisms ...
Neonatal beef calf morbidity and mortality in Missouri
(University of Missouri--Columbia, 2022)
Neonatal morbidity and mortality are major causes of economic loss for US beef cattle producers. The Missouri cattle industry represents 19 percent of the total agriculture sales in the state and is valued at 1.6 billion ...
Diagnosis of aerodigestive disorders in dogs utilizing videofluoroscopic swallow study
(University of Missouri--Columbia, 2022)
An aerodigestive disease (AeroD) is a disorder pathologically linking the respiratory and alimentary tracts. Dogs having respiratory signs without dysphagia, vomiting, or regurgitation typically lack diagnostics identifying ...
A quantitative evaluation of DNA damage from irradiation of feline oral squamous cell carcinoma cells
(University of Missouri--Columbia, 2022)
Feline oral squamous cell carcinoma is a locally invasive neoplasm that continues to carry a poor prognosis despite advances in multimodality oncologic treatment. Location, completeness of surgical excision or complete ...
Evaluation of a relatively hyperosmolar irrigation solution for use in equine femorotibial arthroscopy
(University of Missouri--Columbia, 2022)
Hyperosmolar irrigation solutions have been shown to decrease fluid extravasation during arthroscopic procedures and safety has been demonstrated in canine and human studies. Prospective, blinded, randomized controlled ...