Browsing Biochemistry electronic theses and dissertations (MU) by Thesis Semester "2008 Spring"
Now showing items 1-3 of 3
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Amyloid beta induces cPLA2 activation by an NADPH oxidase-dependent mechanism in neurons
(University of Missouri--Columbia, 2008)Alzheimer's disease (AD) is a neurodegenerative disorder affecting more than 20 million people worldwide. An increase in production of amyloid beta peptides (A[Beta]) and their aggregation to the oligomeric form is thought ... -
A study of SecA: the motor of the bacterial secretion system by site-directed spin labeling and EPR
(University of Missouri--Columbia, 2008)For more than 3 decades, the biochemical details of the Sec system of protein export have been teased out of Escherichia coli. Through these efforts we know that SecA, the ATPase of the Sec system, interacts with several ... -
Substrate activation in the urate oxidase reaction
(University of Missouri--Columbia, 2008)The enzyme urate oxidase (UO) is involved in nitrogen metabolism of many organisms. Urate oxidation is carried out by UO without the aid of a metal ion or cofactor. A catalytic diad has previously been proposed to be ...