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The inhibition of cysteine peptidases improves in vitro maturation of porcine cumulus-oocyte-complexes
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The cell permeable cysteine peptidase inhibitor, E-64, has shown utility as a potent and irreversible inhibitor for many cysteine proteases. Consequently, ...
Analysis of Gbx genes during neural development
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] The understanding of how transcription factors regulate neural patterning in the anterior hindbrain, and how the assembly of specific neuronal circuits ...
Effect of commercial feed additives on production variables and metabolic markers of the periparturient dairy cow
(University of Missouri--Columbia, 2013)
Three experiments were conducted to investigate the effects of commercially available feed additives on production variables and metabolic markers when supplemented during the periparturient period. The hypothesis was that ...
Effects of a commercial feed additive on production losses during acute heat stress conditions in mid-lactation Holstein dairy cows
(University of Missouri--Columbia, 2013)
Heat stress occurs when the environmental temperature exceeds the thermoneutral zone (or comfort zone) of the dairy cow, necessitating the employment of energetically costly cooling mechanisms such as sweating and panting. ...
Effect of endophyte-infected tall fescue on hepatic gene expression in cattle
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Fescue toxicosis may result from the intake of ergot alkaloids found in endophyteinfected (E+) tall fescue. The liver if the major organ involved in ...
Development of laboratory methods to detect meat tenderness
(University of Missouri--Columbia, 2013)
Tenderness has been identified as one of the most important attributes for consumers concerning their meat quality desire, so there is a clear need to accurately determine and grade meat accordingly to tenderness. A ...
Applying effective energy concept for intake prediction and balancing ruminal nitrogen and post-ruminal amino acid requirements for beef cattle
(University of Missouri--Columbia, 2013)
Proper animal nutrition involves balancing nutrient supply to nutrient requirement. Accurate intake prediction is fundamental to diet formulation and appears simple but has historically been challenging to accomplish. ...
Characterization of a transgenic pig model carrying green fluorescent proteasomes
(University of Missouri--Columbia, 2013)
The Ubiquitin Proteasome System (UPS) participates in many biological processes involving substrate-specific proteolysis, and can be linked to various pathologies and genetic diseases. Unfortunately, little is known about ...
Large offspring syndrome, a bovine model for the human loss-of-imprinting overgrowth syndrome Beckwith-Wiedemann
(University of Missouri--Columbia, 2013)
Beckwith-Wiedemann syndrome (BWS) is a human loss-of-imprinting syndrome primarily characterized by macrosomia, macroglossia, and abdominal wall defects. BWS has been associated with misregulation of two clusters of imprinted ...
The effects of reduced protein diets using the Missouri ideal turkey protein on male turkeys from 0 to 21 weeks of age
(University of Missouri--Columbia, 2013)
Protein is one of the major cost components in turkey diets. When diets are formulated on an ideal protein basis, the levels of crude protein decrease with the use of amino acids (AA); performance is maintained and feed ...
Improving fiber by-product utilization in high concentrate diets
(University of Missouri--Columbia, 2013)
The effects of starch and fiber combinations in feedlot diets were examined to determine maximum whole shell corn (WSC) inclusion rate in high fiber diets and determine the effects of fibrolytic enzyme addition to WSC diets ...
Essential oil effects on rumen fermentation, animal performance, and meat quality of beef steers
(University of Missouri--Columbia, 2013)
Efficiency in ruminants has historically been improved by using antibiotics and ionophores to alter rumen fermentation. Nutritionists, however, have begun searching for alternative rumen modifiers due to the negative ...
Abundance of TRIM28, SETDB1, and TP53 mRNA is dynamically regulated during porcine early embryogenesis and is abnormal in preimplantation embryos produced by in vitro fertilization in comparison to in vivo derived and nuclear transfer derived embryos
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] In vitro embryo production is important for research in animal reproduction, embryo transfer, transgenics, and cloning. However, in vitro-derived embryos ...
Use of simvastatin to inhibit advanced prostate cancer formation in the TRAMP mouse model of prostate cancer
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] A provocative question currently proposed by the NIH is: do statin medications, which lower serum cholesterol, prevent cancer? We hypothesize that ...
Overcoming endometriosis-associated preimplantation embryo developmental anomalies by culture
(University of Missouri--Columbia, 2013)
Endometriosis, characterized by the localization and establishment of ectopic endometrial tissue, afflicts 10 to 15% of reproductive-aged women worldwide. Due to the anomalous substances secreted from these endometriotic ...
Stem cells and DNA methylation reprogramming in pigs
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] In mammals, the majority of cells in the body contain the same genome as other cells. The concept of nuclear totipotency has been well demonstrated by ...
Modeling EAA requirement and developing low fishmeal diet for yellow perch
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Overall, my dissertation research sought to enhance production of yellow perch by developing a low cost, complete diet for juvenile yellow perch by ...
Behavioral and physiological phenotype of the viable yellow mouse (AVY/a)
(University of Missouri--Columbia, 2013)
Epigenetics is the study of how heritable phenotypes are transmitted without changes being made to the DNA sequence. One of the best characterized animal models for epigenetics is the viable yellow (Avy) mouse. These animals ...
Generation and characteriazation of porcine induced trophoblast
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Trophoblast stem cells are progenitors of all trophoblast lineages that compose fetal placental portion. Trophoblast stem cells provide an unlimited ...
NIR fluorescent sensors for blood pH and fructose
(University of Missouri--Columbia, 2013)
[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT AUTHOR'S REQUEST.] Blood serum parameters are tightly associated with human beings' physiological activities, therefore the real-time monitoring of blood serum parameters ...